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Postmortem brain abnormalities of the glutamate neurotransmitter system in autism

NeurologyPublished 13 November 2001
Amy E. Purcell, Ok Hee Jeon, Andrew W. Zimmerman, Mary E. Blue, Jonathan Pevsner
Citations497
SJR quartileQ1
SJR score2.40
SNIP1.82

TL;DR

Subjects with autism may have specific abnormalities in the AMPA-type glutamate receptors and glutamate transporters in the cerebellum, which may be directly involved in the pathogenesis of the disorder.

Abstract

Subjects with autism may have specific abnormalities in the AMPA-type glutamate receptors and glutamate transporters in the cerebellum. These abnormalities may be directly involved in the pathogenesis of the disorder.

Keywords

NeuroscienceBiochemistry, Genetics and Molecular Biology