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Comparison of viral burden and phenotype of HIV-1 isolates from lymph nodes and blood

AIDSPublished 1 August 1994
Catherine Tamalet, Alain Lafeuillade, Nouara Yahi, C. Vignoli, Christian Tourrès, Pierre Pellegrino
Citations27
SJR quartileQ1
SJR score1.21
SNIP0.90

TL;DR

The results suggest that the relatively high level of HIV-1 replication in lymph nodes may favour the emergence of viruses exhibiting specific phenotypes, including neutralization escape variants.

Abstract

These results suggest that the relatively high level of HIV-1 replication in lymph nodes may favour the emergence of viruses exhibiting specific phenotypes, including neutralization escape variants. The existence of viral variants in lymphoid tissue at all stages of HIV infection may elucidate certain aspects of the pathogenesis of HIV-1 infection.

Keywords

Immunology and MicrobiologyMedicine