SIMILARITY BETWEEN BEHAVIORAL EFFECTS OF DES-TYROSINE-γ-ENDORPHIN AND HALOPERIDOL AND OF α-ENDORPHIN AND AMPHETAMINE
Elsevier eBooksPublished 1 January 1980
Jan M. van Ree, B. Bohus, D. de Wied
Citations39
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TL;DR
It is suggested that the balance between DTγE and α-endorphin plays a significant role in controlling behavioral responses of the organism.
Abstract
Summary The 4bT-endorphin fragments, des-tyrosine-γ-endorphin (DTγE) and α-endorphin, exert behavioral activities which in some aspects are comparable to those induced by haloperidol and amphetamine respectively. However, the peptides do not mimic the effects of the drugs in particular on gross behavior. It is suggested that the balance between DTγE and α-endorphin plays a significant role in controlling behavioral responses of the organism.
Keywords
NeuroscienceBiochemistry, Genetics and Molecular Biology
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