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Moloney Sarcoma Virus-Induced Tumors in Mice: Inhibition or Stimulation by (Poly rI){middle dot}(Poly rC)

Experimental Biology and MedicinePublished 1 June 1971
Erik De Clercq, T. C. Merigan
Citations53
SJR quartileQ2
SJR score0.86
SNIP0.73

TL;DR

A major effect of age of animals on the effect of (poly rI)·(poly rC) on Moloney sarcoma virus-induced tumors is demonstrated.

Abstract

These studies demonstrate a major effect of age of animals on the effect of (poly rI)·(poly rC) on Moloney sarcoma virus-induced tumors. In 4-6-day-old mice, tumors appeared later in the treated than in the control group, whereas in 20-day-old mice, treatment enhanced tumor formation.

Keywords

Biochemistry, Genetics and Molecular BiologyEnvironmental Science