Cerebral vasculitis associated with cocaine abuse
JAMAPublished 16 October 1987
Brian R. Kaye
Citations147
SJR quartileQ1
SJR score5.35
SNIP10.71
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TL;DR
Cocaine with methamphetamines, heroin, and ephedrine are included in the list of illicit drugs that can cause cerebral vasculitis in men with a history of cocaine abuse.
Abstract
A case of cerebral vasculitis in a previously healthy 22-year-old man with a history of cocaine abuse is described. Cerebral angiograms showed evidence of vasculitis. A search for possible causes other than cocaine produced no results. We now include cocaine with methamphetamines, heroin, and ephedrine as illicit drugs that can cause cerebral vasculitis.
Keywords
MedicineNeurosciencePharmacology, Toxicology and Pharmaceutics
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A case is reported which documents an unusual appearance of intracranial arteries after the intravenous self-administration of methamphetamine (“speed”).
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93 Citations1984Kenneth A. Schwartz, Jerry A. Cohen
A 23-year-old woman was admitted to the hospital with a fivehour history of the sudden onset of intense head, neck, and eye pain after snorting cocaine, and was described as having no prior history of headaches.
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Intracerebral hemorrhage occurred in a 20‐year‐old man following self‐administration of ephedrine and amphetamine, which was typical of vasculitis, and immune complex deposition was found in a skin biopsy.
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Angiographic evidence of vasculitis involving the internal carotid artery was corroborated by autopsy findings, and Amphetamine abuse appears to be causally related to necrotizing angiitis.
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A case of amphetamine-related intracranial haemorrhage and vasculitis, responding to immunosuppressants, is reported, and the importance of Immunosuppressive therapy is discussed.
The Medical Journal of AustraliaCerebral Arteritis Associated with Heroin Abuse
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Investigations revealed right occipital infarction with angiographic changes of arteritis in the posterior cerebral arteries with left homonymous hemianopia after self–administration of heroin.
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