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Microarray Image Processing and Quality Control

The Journal of VLSI Signal Processing Systems for Signal Image and Video TechnologyPublished 24 September 2004
Anton Petrov, Soheil Shams
Citations26

TL;DR

This paper attempts to review microarray image analysis as a whole and to make some experimental comparison of several computational schemes for signal segmentation and measurement extraction.

Abstract

Image processing is an important stage of every microarray experiment. Reliability of this stage strongly influences the results of data analysis performed on extracted gene expressions. Multiple methods related to array recognition, spot segmentation and measurement extraction have emerged in this area over past several years. Currently there are various commercial and freeware packages available, which perform microarray image analysis. This paper attempts to review microarray image analysis as a whole and to make some experimental comparison of several computational schemes for signal segmentation and measurement extraction. Also we provide a detailed discussion of automated image quality control for use with microarray images.

Keywords

Biochemistry, Genetics and Molecular Biology