Estimation of Hit Number
BiometricsPublished 1 September 1971
David W. Alling
Citations10
SJR quartileQ1
SJR score1.26
SNIP1.20
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
Several estimators of h are derived based on the numbers of plaques counted on the series of cell sheets based on serial dilutions of virus particles plated onto susceptible cell sheets.
Abstract
SUMMARY When serial dilutions of a suspension of virus particles are plated onto susceptible cell sheets, plaques of altered cells develop. Plaque formation is initiated by the attachment of a specific number of virus particles to a single cell (the hit number, h). In this paper, several estimators of h are derived based on the numbers of plaques counted on the series of cell sheets.
Keywords
Computer ScienceMathematics
VirologySV40-adenovirus “hybrids”: Presence of two genotypes and the requirement of their complementation for viral replication
51 Citations1966Albert Boeyé, Joseph L. Melnick +1 more
Evidence is presented that the two particles required for the infection of a simian cell are phenotypically similar in that each particle has an adenovirus capsid, but the particles are genotypically different in that SV40-derived genes are carried by only one of them, while the second particle seems to contain only the adenOVirus genome.
BiometrikaThe analysis of Poisson regression with an application in virology
47 Citations1964John J. Gart
Proceedings of the National Academy of SciencesThe genetic heterogeneity of simian virus 40.
28 Citations1967Gerhard Sauer, Hilary Koprowski +1 more
Analyzing the properties of several virus pools by various experimental approaches shows that SV40 pools, in fact, contain mutant particles which undergo an abortive cycle of infection.
BiometricsA Model for the Kinetics of Phage Attachment to Bacteria in Suspension
26 Citations1962D. Yassky
The model proposed is based on a construction of a set of differential equations describing the rates of change of concentrations of the various possible particles, among which the non-degenerate ones are similar to the Binomial, the Geometric and the Poisson distributions.
JAMATransformation of Cells in Vitro by DNA-Containing Viruses
26 Citations1964Renato Dulbecco
Virus-induced transformation is a tool for studying certain aspects of important and obscure phenomena, including differentiation and carcinogenesis, which are of considerable interest today.
BiometricsMaximum Likelihood Estimation of Survival Curve Parameters
19 Citations1968Edward L. Frome, John J. Beauchamp
A weighted least squares procedure, which gives estimates equivalent to the maximum likelihood estimates, is presented, and tests of the model and of the assumed distribution of the observations are given.
PubMedA study of fowl pox virus titration on the chorioallantosis by the pock counting technique.
18 Citations1949D. B. W. Reid, J. F. Crawley +1 more
Proceedings of the National Academy of SciencesThe influence of dilution on the probability of multiple infection of cells by virus particles of different types.
9 Citations1967Miranda Pring
BiometricsEstimation of the Number of Critical Sites in Limited Genome Expression During Viral Infection of Bacteria
1 Citations1969Jean Dickinson Gibbons, Samuel Litwin
The probability of wild expression, hence viable phage progeny, is found here as a function of k and the two multiplicities of infection, and the effect of the postulated number of expressive sites is clearly demonstrated.