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Nervous System-Immune System Communication

Clinical Infectious DiseasesPublished 1 January 1991
Barry G. W. Amason
Citations21
SJR quartileQ1
SJR score2.99
SNIP2.01

TL;DR

This essay is based on the premise that certain individuals may have a biologically determined propensity to respond to infection that is manifested by the development of disease such as chronic fatigue syndrome; the sequence of events that leads to this response involves the immune system.

Abstract

This essay is based on the premise that certain individuals may have a biologically determined propensity to respond to infection that is manifested by the development of disease such as chronic fatigue syndrome; the sequence of events that leads to this response involves the immune system. Biochemical pathways between the immune and nervous systems are reviewed, and the role of various products in the systemic circulation, including interleukin-1, pituitary hormone, and catecholamines, is highlighted. This premise could be tested by measuring levels of these substances in carefully selected patients and controls.

Keywords

MedicineNeuroscienceBiochemistry, Genetics and Molecular Biology