Improved grading of bone tumors with the monoclonal antibody Ki-67
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TL;DR
The monoclonal antibody Ki-67 was found to be a handy and reliable tool for improved grading of bone tumors and compatible with flow cytometric and autoradiographic studies on similar tumor entities.
Abstract
A total of 60 bone tumors and tumor-like lesions presenting various grades of malignancy were investigated immunohistologically with the monoclonal antibody Ki-67 directed against a cell proliferation-associated nuclear antigen. The results obtained agree well with those of flow cytometric and autoradiographic studies on similar tumor entities. The monoclonal antibody Ki-67 was found to be a handy and reliable tool for improved grading of bone tumors.