High-Resolution NMR Spectroscopy of Membrane Proteins in Aligned Bicelles
Journal of the American Chemical SocietyPublished 6 November 2004
Anna A. De Angelis, Alexander A. Nevzorov, Sang Ho Park, Stanley C. Howell, Anthony A. Mrse, Stanley J. Opella
Citations105
SJR quartileQ1
SJR score5.55
SNIP2.61
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TL;DR
High-resolution solid-state NMR spectra can be obtained from uniformly (15)N-labeled membrane proteins in magnetically aligned bicelles that contain the orientational information necessary for protein structure determination.
Abstract
High-resolution solid-state NMR spectra can be obtained from uniformly (15)N-labeled membrane proteins in magnetically aligned bicelles. Fast uniaxial diffusion about the axis of the bilayer normal results in single-line spectra that contain the orientational information necessary for protein structure determination.
Keywords
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