Improved Estimation of Secondary Structure in Ribonucleic Acids
Nature New BiologyPublished 1 November 1973
Ignacio Tinoco, Philip N. Borer, Barbara Dengler, Mark Levine, Olke C. Uhlenbeck, Donald M. Crothers
Citations2,287
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TL;DR
This method can be used for predicting and assessing possible secondary structures for recently determined RNA sequences and new experimental and theoretical results allow us to improve the method, without making it more complicated.
Abstract
A SIMPLE method for estimating the most stable secondary structure of an RNA molecule from its sequence was proposed earlier1. This method can be used for predicting and assessing possible secondary structures for recently determined RNA sequences2–4. New experimental5–8 and theoretical9, 10 results allow us to improve the method, without making it more complicated.
Keywords
MedicineBiochemistry, Genetics and Molecular Biology
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