A paradoxical sleep-dependent window for memory 53–56 h after the end of avoidance training

PsychobiologyPublished 1 June 1993Open access

Carlyle Smith, Christine MacNeill

DOI10.3758/bf03332034

Citations23

Abstract

Sprague-Dawley rats ( N =56) were trained in a two-way shuttle shock-avoidance task (50 trials/day for 2 consecutive days). Subjects were then assigned to one of six paradoxical sleep deprivation (PSD) groups or a non-PSD control group. Each test group was subjected to PSD for one of the following 4-h periods: Hours 49–52, 53–56, 57–60, 61–64, 65–68, or 69–72 after the last training trial. Retesting was done 7 days after the end of training. Memory loss was observed when the PSD was applied between 53 and 56 hours after the end of training but nowhere else. It was concluded that a vulnerable window for memory, requiring PS, exists during Hours 53–56 after the end of training in the shuttle avoidance task.

Keywords

MedicineNeuroscience

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