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High prevalence of hyperuricaemia and gout in an urbanised Micronesian population.

BMJPublished 13 May 1978Open access
Paul Zimmet, S Whitehouse, Livia Jackson, K Thoma
Citations37
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TL;DR

The prevalence of hyperuricaemia and gout was investigated in the Micronesian inhabitants of the highly urbanised central Pacific island of Nauru, finding the high prevalence rates may be related to the environmental change from the traditional island style of living to one of almost complete Westernisation.

Abstract

The prevalence of hyperuricaemia and gout was investigated in the Micronesian inhabitants of the highly urbanised central Pacific island of Nauru. Sixty-four per cent of men and 60% of women aged 20 years and over had hyperuricaemia--the highest prevalence rates yet reported for a population. The hyperuricaemia in men was accompanied by a high prevalence of clinical gout (6.9%). While the hyperuricaemia is probably genetic, the high prevalence of gout may be related to the environmental change from the traditional island style of living to one of almost complete Westernisation.

Keywords

MedicineBiochemistry, Genetics and Molecular Biology