Network Medicine — From Obesity to the “Diseasome”
New England Journal of MedicinePublished 25 July 2007
Albert-Ĺaszló Barabási
Citations533
SJR quartileQ1
SJR score19.08
SNIP13.47
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TL;DR
A recent study reported that among people who carried a single copy of the high-risk allele for the FTO gene, which is associated with fat mass and obesity, the risk of obesity increased by 30%.
Abstract
A recent study reported that among people who carried a single copy of the high-risk allele for the FTO gene, which is associated with fat mass and obesity, the risk of obesity increased by 30%. The risk of obesity increased by 67% among people who carried two alleles, and on average they gained 3.0 kg (6.6 lb) or more.1 Given that approximately one sixth of the population of European descent is homozygous for this allele, this link between the FTO gene and obesity appears to be one of the strongest genotype–phenotype associations detected by modern genome-screening techniques.That obesity has . . .
Keywords
Biochemistry, Genetics and Molecular Biology
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