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Smoking-Cessation Treatment Combining Transdermal Nicotine Substitution with Behavioral Therapy

PharmacopsychiatryPublished 1 May 1991
Gerhard Buchkremer, E Minneker, Matthew S. Block
Citations41
SJR quartileQ1
SJR score0.94
SNIP1.20

TL;DR

Results showed that the nicotine concentration in the patch, special relapse prevention methods, and the type of dosage had no influence on therapeutic success, and nicotine concentration played a decisive role in the compatibility of the patch.

Abstract

Effects of smoking-cessation treatment combining transdermal nicotine substitution with behavioral therapy were investigated in two studies. A total of 403 smokers underwent nine weeks of behavioral self-control treatment. For seven weeks, groups with transdermal nicotine substitution were also provided with nicotine patches that continuously release nicotine through the skin into the circulatory system. The effects of treatment were measured by total abstinence. The results showed that the nicotine concentration in the patch, special relapse prevention methods, and the type of dosage (individual versus fixed dose) had no influence on therapeutic success. Nicotine concentration played a decisive role in the compatibility of the patch. Combining transdermal nicotine substitution with behavioral therapy produced 12-month success rates (total abstinence) of about 35%.

Keywords

Biochemistry, Genetics and Molecular Biology