Transposable genetic elements and plasmid evolution
NaturePublished 1 October 1976
Stanley N. Cohen
Citations305
SJR quartileQ1
SJR score18.29
SNIP10.16
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TL;DR
Transposable elements of DNA that are structurally defined and genetically discrete units seem to have an important role in the evolution of bacterial plasmids and serve as novel biological switches capable of turning on and off the expression of nearby genes as a consequence of their insertion into or excision from plasmid genomes.
Abstract
Transposable elements of DNA that are structurally defined and genetically discrete units seem to have an important role in the evolution of bacterial plasmids. Recombination occurring at the termini of such elements can result in the joining together of unrelated DNA segments that lack extensive nucleotide sequence homology. In addition, transposable elements serve as novel biological switches capable of turning on and off the expression of nearby genes as a consequence of their insertion into or excision from plasmid genomes.
Keywords
Immunology and MicrobiologyBiochemistry, Genetics and Molecular BiologyEnvironmental Science
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