Regional versus systemic chemotherapy in the treatment of colorectal carcinoma metastatic to the liver: Is there a survival difference?--Meta-analysis of the published literature
CancerPublished 15 October 1996
Athanasios Harmantas, Lorne Rotstein, Bernard Langer
Citations166
SJR quartileQ1
SJR score2.95
SNIP1.90
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TL;DR
A meta‐analysis of the literature was undertaken to determine if regional infusion chemotherapy using either 5‐fluorouracil or floxuridine (FUDR) confers a survival advantage over systemic chemotherapy for the treatment of metastatic colorectal carcinoma confined to the liver.
Abstract
Based on this meta-analysis, it appears that hepatic artery infusion chemotherapy confers a modest survival benefit over systemic chemotherapy. Whether this is clinically relevant depends on the quality rather than just the duration of survival.
Keywords
Medicine
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