Deliveries and children born after in-vitro fertilisation in Sweden 1982–95: a retrospective cohort study
The LancetPublished 1 November 1999
T. Bergh, A Ericson, Torbjörn Hillensjø, Nygren Kg, U. B. Wennerholm
Citations663
SJR quartileQ1
SJR score12.11
SNIP22.72
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
A high frequency of multiple births and maternal characteristics were the main factors that led to adverse outcomes, and not the in-vitro-fertilisation technique itself, which needs to be changed to lower the rate of multiple pregnancy.
Abstract
A high frequency of multiple births and maternal characteristics were the main factors that led to adverse outcomes, and not the in-vitro-fertilisation technique itself. The clinical practice of in-vitro-fertilisation needs to be changed to lower the rate of multiple pregnancy.
Keywords
MedicineBiochemistry, Genetics and Molecular Biology
Scandinavian Journal of Social MedicineA Quality Study of a Medical Birth Registry
993 Citations1990Sven Cnattingius, Anders Ericson +2 more
A quality control study was made of the Swedish Medical Birth Registry, which used one mode of data collection during 1973-1981 and another from 1982 onwards.
BMJTwins, triplets, and cerebral palsy in births in Western Australia in the 1980s.
435 Citations1993Beverly Petterson, Kristi Nelson +2 more
Triplet pregnancies produced a child with cerebral palsy 47 times more often than singleton pregnancies did and twin pregnancies eight times moreOften, as multiple births are increasing mainly because of personal and medical decisions the increased risk of cerebral palsies in multiple births is of concern.
Pflügers Archiv - European Journal of PhysiologyBeiträge zur Physiologie und Pathologie der Mehrlingsgeburten beim Menschen
273 Citations1901Wilhelm Weinberg
Human ReproductionProspective follow-up study of 877 children born after intracytoplasmic sperm injection (ICSI), with ejaculated epididymal and testicular spermatozoa and after replacement of cryopreserved embryos obtained after ICSI
195 Citations1996M Bonduelle, Ann Wilikens +6 more
There seems to be no higher incidence of congenital malformations in children born after ICSI, and a slight increase in de-novo chromosomal aberrations and the higher frequency of transmitted chromosomalAberrations is probably linked directly to the characteristics of the infertile men treated rather than to the ICSi procedure itself.
Human ReproductionPreterm delivery, low birthweight and small-for-gestational-age in liveborn singleton babies resulting from in-vitro fertilization
149 Citations1992Pat Doyle, Valerie Beral +1 more
Investigation of possible risk factors for prematurity, low birthweight and small-for-gestational-age (SGA) in singleton IVF births in Great Britain indicated that hypertension during pregnancy was an independent risk for preterm delivery, low Birthweight and SGA, and the number of embryos transferred and the type of infertility for low birth Weight.
Obstetrics and GynecologyObstetric Outcome in Singleton Pregnancies After Assisted Reproduction
145 Citations1995Tom Tanbo
Singleton pregnancies resulting from assisted reproduction represent obstetric risk cases, and the patients should be offered special attention during the pregnancy, which will probably be their only one.
Fertility and SterilityIs the obstetric outcome of in vitro fertilized singleton gestations different from natural ones? A controlled study
141 Citations1997Benjamin Reubinoff, Arnon Samueloff +4 more
When controlling for maternal age, parity, ethnic origin, and location and date of delivery, singleton IVF pregnancies do not carry an increased risk for prematurity, low birth weight, or maternal or fetal complications.
Human ReproductionMinor congenital anomalies, major congenital malformations and development in children conceived from cryopreserved embryos
140 Citations1995Alastair Sutcliffe, S.W. D’Souza +4 more
Cryopreserved embryo group results are reassuring in that the minor congenital anomaly and major congenital malformation rates were similar to those in normally conceived children of a similar age, sex and social class and their development was not adversely affected by cryopreservation.
Fertility and SterilityDelivery outcome after infertility—a registry study
140 Citations1991Husam A. Ghazi, Clary Spielberger +1 more
Among a total of 379,779 women with 383,589 infants born in Sweden (1983 to 1986), 7.8% had a recorded period of infertility of at least 1 year, and Singleton infants showed an increased percentage of low-birth weight infants, short gestational duration, and signs of intrauterine growth retardation.
Fertility and SterilityPregnancies and births resulting from in vitro fertilization: French national registry, analysis of data 1986 to 1990
140 Citations1995FIVNAT
Ass conception frequently results in multiple pregnancy, and this is the main determinant of pregnancy outcome, but it is not the only risk factor for prematurity, which is also more frequent among IVF singleton newborn.
Journal of Epidemiology & Community HealthCongenital malformations in twins in England and Wales.
133 Citations1991Pat Doyle, Valerie Beral +2 more
Several major malformations were significantly more common in twins than in singletons, and the excess of indeterminate sex and pseudohermaphroditism may be analogous to freemartinism in cattle.
The LancetPostnatal growth and health in children born after cryopreservation as embryos
131 Citations1998Ulla‐Britt Wennerholm, Kerstin Albertsson‐Wikland +8 more
The cryopreservation process does not adversely affect the growth and health of children during infancy and early childhood, and the prevalence of chronic diseases did not differ between the three groups.
Human ReproductionIn-vitro fertilization pregnancies and perinatal health in Finland 1991–1993
117 Citations1995Mika Gissler, Maili Malin Silverio +1 more
The purpose of this study was to compare IVF mothers with other mothers, and the perinatal health and health care costs of IVF infants to those of other infants, and found that both IVF singletons and multiples had poorer health than other infants.
Fertility and SterilityAssisted reproductive technology in the united states: 1996 results generated from the american society for reproductive medicine/society for assisted reproductive technology registry
98 Citations1999The American Society for Reproductive Medicine
In 1996, there were more programs reporting ART treatment and a significant increase in reported cycles, and overall average success rates exhibited an actual increase of 3.5% (this is an increase of 15.8% when compared to the success rate for 1995).
Human ReproductionThe obstetric outcome of singleton pregnancies following in-vitro fertilization/gamete intra-Fallopian transfer
97 Citations1994Jim X. Wang, Anne M. Clark +5 more
The excess risk of delivering a SGA/VSGA baby and pre-term delivery from an IVF/GIFT pregnancy seems to be largely confined to women with unexplained infertility and young primiparae.
Journal of Assisted Reproduction and GeneticsPerinatal Outcome of Pregnancies After Assisted Reproduction: A Case–Control Study
93 Citations1997Marc Dhont, F. De Neubourg +2 more
It is concluded that the perinatal outcome of ART singleton pregnancies is not different from that in matched controls, and ART twin pregnancies showed a higher incidence of preterm deliveries than control pregnancies and needed more neonatal intensive care.
Acta geneticae medicae et gemellologiae twin researchCongenital Malformations in Twins: A Population Study
93 Citations1986Bëngt Källén
An excess was noticed in twins in the rates of cardiac defects, spine defects, gut atresias--notably esophageal and anal atresia--and severe kidney malformations, components of the so-called VACTERL syndrome, being more common in twins than in singletons, though statistical significance was not reached.
Human ReproductionBirths in Israel resulting from in-vitro fertilization/embryo transfer, 1982–1989: National Registry of the Israeli Association for Fertility Research
87 Citations1992Shevach Friedler, S. Mashiach +1 more
A survey of published national IVF registries from Australia and New Zealand, Great Britain, USA and France showed much similarity in all aspects of pregnancy outcome following IVF and related technologies.
Reproductive ToxicologyAn international collaborative study of the epidemiology of esophageal atresia or stenosis
82 Citations1993Elisabeth Robert, Osvaldo M. Mutchinick +7 more
Infant survival varied among programs and depended heavily on associated malformations, and a large proportion entered the constellation sometimes called "caudal mesoderm spectrum of mal Formations": VATER, Potter, and caudal regression sequences.
BMJHigh incidence of preterm births and early losses in pregnancy after in vitro fertilisation. Australian in vitro fertilisation collaborative group.
79 Citations1985C Wood, A Trounson +28 more
PubMed[Pregnancy, births and infants after in-vitro-fertilization in Norway, 1988-1991].
11 Citations1995Vidar von Dûring, Jan Martin Maltau +7 more
The proportion of multiple births should be reduced in pregnancies after in vitro fertilization in Norway, and the relative risk of stillbirth and death during the first year of life is adjusted for maternal age and birth order.
The epidemiology of multiple births
8 Citations2006J. Orlebeke A. Eriksson R. Derom
