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Randomized Trial of Folic Acid Supplementation and Serum Homocysteine Levels

Archives of Internal MedicinePublished 12 March 2001
David S Wald, Lucy Bishop, Nicholas Wald, Matthew Law, Enid Hennessy, Donald G. Weir
Citations200

TL;DR

A dosage of folic acid of 0.8 mg/d appears necessary to achieve the maximum reduction in serum homocysteine level across the range of homocy steine levels in the population, indicating that monitoring of the reduction in an individual is impractical.

Abstract

A dosage of folic acid of 0.8 mg/d appears necessary to achieve the maximum reduction in serum homocysteine level across the range of homocysteine levels in the population. Current US food fortification levels will achieve only a small proportion of the achievable homocysteine reduction.

Keywords

MedicineEnvironmental Science