Protein arrays and microarrays
Current Opinion in Chemical BiologyPublished 1 February 2001
Heng Zhu, M Snyder
Citations354
SJR quartileQ1
SJR score2.06
SNIP1.23
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TL;DR
New protein-microarray technologies have been introduced that enable the high-throughput analysis of protein activities that have the potential to revolutionize the analysis of entire proteomes.
Abstract
In the past, studies of protein activities have focused on studying a single protein at a time, which is often time-consuming and expensive. Recently, with the sequencing of entire genomes, large-scale proteome analysis has begun. Arrays of proteins have been used for the determination of subcellular localization, analysis of protein-protein interactions and biochemical analysis of protein function. New protein-microarray technologies have been introduced that enable the high-throughput analysis of protein activities. These have the potential to revolutionize the analysis of entire proteomes.
Keywords
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