The B-cell antigen receptor complex: structure and signal transduction
Immunology TodayPublished 1 September 1994
Christopher M. Pleiman, Daniele D’Ambrosio, John C. Cambier
Citations203
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TL;DR
New findings regarding BCR structure and signal transduction are consolidated and the compartmentalization of function within this extremely versatile hetero-oligomeric receptor complex is consolidated.
Abstract
The specificity of the immune response is determined by the interaction between the B-cell receptor (BCR) and its cognate structure, antigen. Recent studies have provided considerable insight into the compartmentalization of function within this extremely versatile hetero-oligomeric receptor complex. In this article, Christopher Pleiman, Daniele D'Ambrosio and John Cambier consolidate new findings regarding BCR structure and signal transduction.
Keywords
Immunology and MicrobiologyMedicine
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