ROBOTS AS SOCIAL ACTORS: AURORA AND THE CASE OF AUTISM
European Journal of Clinical InvestigationPublished 1 January 1999
Kerstin Dautenhahn
Citations198
SJR quartileQ1
SJR score1.17
SNIP0.99
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
Allogeneic haematopoietic stem cell transplantation (alloSCT) often remains the only curative therapy for hematologic malignancies and endothelial dysfunction was identified as a major contributor to NRM.
Abstract
Together, these data suggest that SEP improves NRM and OS post-alloSCT in particular in patients with intermediate endothelial risk and provide first mechanistic clues about its potential mode of action.
Keywords
PsychologyComputer ScienceNeuroscience
CognitionDoes the autistic child have a “theory of mind” ?
8,438 Citations1985Simon Baron‐Cohen, Alan M. Leslie +1 more
A new model of metarepresentational development is used to predict a cognitive deficit which could explain a crucial component of the social impairment in childhood autism.
Applied ErgonomicsDesigning the user interface: Strategies for effective human-computer interaction
5,616 Citations1993
The Intentional Stance
3,862 Citations1987Daniel C. Dennett
TransplantationCLINICAL MANIFESTATIONS OF GRAFT-VERSUS-HOST DISEASE IN HUMAN RECIPIENTS OF MARROW FROM HL-A-MATCHED SIBLING DONOR,S
3,672 Citations1974Harold Glucksberg, Rainer Storb +6 more
The results show that despite histocompatibility matching and methotrexate therapy, GVHD remains a serious and often fatal complication of marrow transplantation.
Medical Entomology and ZoologyMachiavellian Intelligence: Social Expertise and the Evolution of Intellect in Monkeys, Apes, and Humans
1,693 Citations1988Richard W. Byrne, Andrew Whiten
LeonardoMind Children: The Future of Robot and Human Intelligence
1,276 Citations1991Fred Truck, Hans Moravec
European Journal of Clinical InvestigationA catalogue of reporting guidelines for health research
1,048 Citations2009Iveta Simera, David Moher +3 more
Watch what I do: programming by demonstration
1,024 Citations1993Allen Cypher, Daniel C. Halbert +5 more
Part 1 Systems: Pygmalion tinker a predictive calculator rehearsal world smallStar peridot metamouse TELS eager garnet the Turvy experience chimera the geometer's sketchpad tourmaline a history-based macro by example system mondrian triggers the AIDE project.
Cell Death and DifferentiationT cell apoptosis by tryptophan catabolism
1,014 Citations2002Francesca Fallarino, Ursula Grohmann +6 more
It is shown that tryptophan metabolites in the kynurenine pathway, such as 3-hydroxyanthranilic and quinolinic acids, will induce the selective apoptosis in vitro of murine thymocytes and of Th1 but not Th2 cells, suggesting that the selective deletion of T lymphocytes may be a major mechanism whereby tryptophile metabolism affects immunity under physiopathologic conditions.
Social learning in animals : the roots of culture
952 Citations1996Cecilia Heyes, Bennett G. Galef
Social Learning: B.G. Galef, Jr., Social Enhancement of Food Preferences in Norway Rats: A Brief Review, and C.M. Heyes, Genuine Imitation?
Cancer ResearchTryptophan Catabolism in Cancer: Beyond IDO and Tryptophan Depletion
697 Citations2012Michael Platten, Wolfgang Wick +1 more
This review summarizes the exciting developments in the understanding of tryptophan catabolism as a key factor in the immunobiology of cancer.
Oxford University Press eBooksThe Thinking ApeEvolutionary Origins of Intelligence
663 Citations1995Richard W. Byrne
The limits of fossil evidence are revealed and the reconstruction of evolution is reconstructed, including Machiavellian intelligence, which shows how animals learn better in social groups and how to plan and think ahead.
Trends in Molecular MedicinePleiotropic effects of statin therapy: molecular mechanisms and clinical results
588 Citations2008Chao-Yung Wang, Ping‐Yen Liu +1 more
Data from recent clinical trials are reviewed that support the concept of statin pleiotropy and provide a rationale for their clinical importance.
Communications of the ACMCredibility and computing technology
588 Citations1999Shawn Tseng, B. J. Fogg
Key terms are defined, key terms are summarized, knowledge on computer credibility is summarized, and frameworks for understanding issues in this domain are suggested.
Lecture notes in computer scienceThe Cog Project: Building a Humanoid Robot
569 Citations1999Rodney A. Brooks, Cynthia Breazeal +3 more
This chapter gives a background on the methodology that the authors have used in investigations, highlights the research issues that have been raised during this project, and provides a summary of both the current state of the project and the long-term goals.
Autism as an executive disorder
476 Citations1997James A. Russell
This chapter discusses the neurobiological and neurophysical dimensions of autism and how executive disorders can bring about an inadequate "theory of mind" in autism.
Biology of Blood and Marrow TransplantationBlood and Marrow Transplant Clinical Trials Network Toxicity Committee Consensus Summary: Thrombotic Microangiopathy after Hematopoietic Stem Cell Transplantation
455 Citations2005Vincent T. Ho, Corey Cutler +7 more
The toxicity committee of the Blood and Marrow Transplant Clinical Trials Network has reviewed the current literature on transplant-related HUS/TTP and recommends that it be henceforth renamed posttransplantation thrombotic microangiopathy (TMA), an operational definition for TMA based on the presence ofmicroangiopathic hemolysis and renal and/or neurologic dysfunction.
New England Journal of MedicineST2 as a Marker for Risk of Therapy-Resistant Graft-versus-Host Disease and Death
399 Citations2013Mark T. Vander Lugt, Thomas Braun +16 more
ST2 levels measured at the initiation of therapy for GV HD and during the first month after transplantation improved risk stratification for treatment-resistant GVHD and death without relapse after transplanting.
HaematologicaDiagnostic criteria for hematopoietic stem cell transplant-associated microangiopathy: results of a consensus process by an International Working Group
394 Citations2007Tapani Ruutu, Giovanni Barosi +15 more
The Working Group recommends that the presented criteria for diagnosing clinically significant TAM be adopted in clinical use, especially in scientific trials.
Frontiers in ImmunologyTryptophan Metabolism in Inflammaging: From Biomarker to Therapeutic Target
384 Citations2019Freek J. H. Sorgdrager, Petrus J.W. Naudé +3 more
How age-related Kyn/Trp activation is necessary to control inflammaging and alters the functioning of other metabolic faiths of Trp including Kyn metabolites, microbiota-derived indoles and nicotinamide adenine dinucleotide (NAD+).
CancerRisk score for outcome after allogeneic hematopoietic stem cell transplantation
373 Citations2009Aloïs Gratwohl, Martin Stern +11 more
The European Group for Blood and Marrow Transplantation risk score, previously established for chronic myeloid leukemia, could be used to predict outcome after allogeneic hematopoietic stem cell transplantation for hematological disease in general.
Communications of the ACMToward an ethics of persuasive technology
359 Citations1999Daniel Berdichevsky, Erik Neuenschwander
The exploration of the ethics of persuasive technologies seeks to begin establishing a first set of principled guidelines for their design and implementation.
The Journal of ImmunologyIDO Upregulates Regulatory T Cells via Tryptophan Catabolite and Suppresses Encephalitogenic T Cell Responses in Experimental Autoimmune Encephalomyelitis
355 Citations2010Yaping Yan, Guang-Xian Zhang +7 more
The hypothesis that IDO induces the generation of Tregs via tryptophan metabolites, such as 3-HAA, which enhances TGF-β expression from DCs and promotes Treg differentiation is supported.
British Journal of CancerThe therapeutic potential of targeting tryptophan catabolism in cancer
300 Citations2019Christiane A. Opitz, Luis F. Somarribas Patterson +5 more
This review will discuss strategies to target Trp-degrading enzymes and possible down-stream consequences of their inhibition, and provide comprehensive background information on Trp catabolic enzymes as targets in immuno-oncology and their current state of development.
The American Journal of CardiologyEffects of Statins on 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibition Beyond Low-Density Lipoprotein Cholesterol
299 Citations2005James K. Liao
Recent studies indicate that some of the cholesterol-independent or "pleiotropic" effects of statins involve improving endothelial function, enhancing the stability of atherosclerotic plaques, decreasing oxidative stress and inflammation, and inhibiting the thrombogenic response.
Molecular PsychiatryDysregulation of kynurenine metabolism is related to proinflammatory cytokines, attention, and prefrontal cortex volume in schizophrenia
290 Citations2019Jochen Kindler, Chai K. Lim +11 more
Further evidence is provided for the role of inflammation in a subgroup of patients with schizophrenia and a molecular mechanism through which inflammation could lead to schizophrenia is suggested.
AngiogenesisAngiopoietin-2 as a marker of endothelial activation is a good predictor factor for intensive care unit admission of COVID-19 patients
257 Citations2020David M. Smadja, Coralie L. Guérin +21 more
Angiopoietin-2 is a relevant predictive factor for ICU direct admission in COVID-19 patients with criteria of hospitalization for referral to intensive care unit (ICU) and/or respiratory worsening, and this result showing an endothelial activation reinforces the hypothesis of a CO VID-19-associated microvascular dysfunction.
Applied Artificial IntelligenceTHE ART OF DESIGNING SOCIALLY INTELLIGENT AGENTS: SCIENCE, FICTION, AND THE HUMAN IN THE LOOP
237 Citations1998Kerstin Dautenhahn
Social intelligent agents (SIAs) are understood to be agents that do not only from an observer point of view behave socially but that are able to recognize and identify other agents and establish and maintain relationships to other agents.
Blood AdvancesHow much has allogeneic stem cell transplant–related mortality improved since the 1980s? A retrospective analysis from the EBMT
213 Citations2020Olaf Penack, Christophe Peczynski +10 more
Transplantation-related mortality has decreased significantly in the past 40 years, and favorable data facilitate evidence-based treatment decisions on transplantation indications in the context of the availability of novel immunotherapies.
BloodSteroid-refractory GVHD: T-cell attack within a vulnerable endothelial system
196 Citations2011Thomas Luft, Sascha Dietrich +9 more
It is suggested that endothelial cell vulnerability and dysfunction, rather than refractory T-cell activity, drives treatment refractoriness of GVHD and opens new avenues for prediction and control of this devastating condition.
The Lancet HaematologyEASIX in patients with acute graft-versus-host disease: a retrospective cohort analysis
192 Citations2017Thomas Luft, Axel Benner +9 more
In patients with reduced-intensity conditioning, EASIX-GVHD is a powerful predictor of survival after GVHD, and could be the future basis for development of risk-adapted GV HD treatment strategies.
Medical Entomology and ZoologyTreatment of Autistic Children
184 Citations1987Patricia Howlin, Michael Rutter
Nature ImmunologyIDO: more than an enzyme
178 Citations2011Wanjun Chen
In addition to its recognized function as an enzyme that catalyzes tryptophan, indoleamine 2,3-dioxygenase (IDO) acts as an intracellular signal transducer, in response to transforming growth factor-β, to induce a stably regulatory phenotype in plasmacytoid dendritic cells.
Clinical Journal of the American Society of NephrologyRenal Thrombotic Microangiopathy after Hematopoietic Cell Transplant
176 Citations2009Siribha Changsirikulchai, David Myerson +4 more
TMA in HCT recipients is associated with acute GVHD grades II to IV, recipient/donor mismatch, TBI > 1200 cGy, and adenovirus infection.
Bone Marrow TransplantationEASIX and mortality after allogeneic stem cell transplantation
160 Citations2019Thomas Luft, Axel Benner +13 more
This study establishes EASIX-pre based on a standard laboratory biomarker panel as a predictor of individual risk of mortality after alloSCT independently from established clinical criteria.
Oxford University Press eBooksTowards an executive dysfunction account of repetitive behaviour in autism
156 Citations2015Michelle Turner
Journal of Allergy and Clinical ImmunologyStatins enhance the anti-inflammatory effects of inhaled corticosteroids in asthmatic patients through increased induction of indoleamine 2, 3-dioxygenase
153 Citations2010Kittipong Maneechotesuwan, Wuttichai Ekjiratrakul +3 more
A statin enhances the anti-inflammatory effect of an inhaled corticosteroid in asthma, and this was mediated through the alteration of IDO activity in macrophages.
A motivational system for regulating human-robot interaction
150 Citations1998Cynthia Breazeal
A motivational system for an autonomous robot which is designed to regulate human-robot interaction and implements drives, emotions, and facial expressions in order to engage in meaningful bi-directional social interactions with humans.
Applied Artificial IntelligenceGetting personal with computers: How to design personalities for agents
137 Citations1999D. Christopher Dryer
To design personalities for social agents, it is necessary to consider the nature of personality and its role in interactions between people and artifacts.
Cybernetics & SystemsI COULD BE YOU: THE PHENOMENOLOGICAL DIMENSION OF SOCIAL UNDERSTANDING
135 Citations1997Kerstin Dautenhahn
The author's general hypothesis is that complex forms of social understanding that biological agents especially humans show are based on two mechanisms: 1 the bodily, experiential dynamics of emphatic resonance and 2 the biographic reconstruction of a communication situation.
Personality-rich believable agents that use language
134 Citations1997A. Bryan Loyall, Joseph Bates
Hap, the behavior-based architecture used by the Oz group to construct non-linguistic believable agents, is extended to support natural language text generation, to tightly integrate text generation with other aspects of the agent, including action, perception, inference and emotion.
Applied Artificial IntelligenceFROM PERCEPTION-ACTION LOOPS TO IMITATION PROCESSES: A BOTTOM-UP APPROACH OF LEARNING BY IMITATION
133 Citations1998Philippe Gaussier, Sorin Moga +2 more
A neural architecture for a robot in order to learn how to imitate a sequence of movements performed by another robot or by a human is proposed, allowing the student robot to discover by itself solutions to a particular problem or to learn from another robot what to do.
Elsevier eBooksThe Human Infant as Imitative Generalist: A 20-Year Progress Report on Infant Imitation with Implications for Comparative Psychology
130 Citations1996Andrew N. Meltzoff
This chapter suggests that reciprocal imitation games between parent and offspring provide ontogenetic roots for the growth of theory of mind in human children.
Molecular Medicine ReportsIndoleamine 2, 3-dioxygenase regulation of immune response (Review)
117 Citations2018Hao Wu, Jianping Gong +1 more
Evaluating how catabolism of tryptophan regulated by IDO modulates the immune response to inflammatory and immunological signals finds that blocking this pathway may be a novel adjuvant therapeutic strategy for clinical application in immunotherapy.
Lecture notes in computer scienceCreating Personalities for Synthetic Actors
114 Citations1997Robert Trappl, Paolo Petta
Designing the User Interface. Strategies for Effective Human-Computer Interaction
110 Citations1992Ben Schneiderman
This third edition of Ben Shneiderman's introduction to user- interface design contains expanded and earlier coverage of development methodologies, evaluation techniques, and user-interface building tools.
BloodPreemptive HMG-CoA reductase inhibition provides graft-versus-host disease protection by Th-2 polarization while sparing graft-versus-leukemia activity
98 Citations2007Robert Zeiser, Sawsan Youssef +4 more
AT has significant protective impact on aGVHD lethality by Th-2 polarization and inhibition of an uncontrolled Th-1 response while maintaining GVL activity, which is of great clinical relevance given the modest toxicity profile of AT.
Bone Marrow TransplantationTransplant-associated thrombotic microangiopathy is an endothelial complication associated with refractoriness of acute GvHD
83 Citations2017Markus Zeisbrich, Natália Becker +8 more
Evidence is provided that transplant-associated thrombotic microangiopathy contributes to the pathogenesis of aGvHD refractoriness and patients with an increased TMA risk can be identified pretransplant and may benefit from pharmacological endothelium protection.
Biology of Blood and Marrow TransplantationImproved Survival with Ursodeoxycholic Acid Prophylaxis in Allogeneic Stem Cell Transplantation: Long-Term Follow-Up of a Randomized Study
81 Citations2013Tapani Ruutu, Eeva Juvonen +7 more
The long-term results of a prospective randomized study on the use of ursodeoxycholic acid (UDCA) for prevention of hepatic complications after allogeneic stem cell transplantation continue to support the useful role of UDCA in the prevention of transplant-related complications inallogeneic transplantation.
HaematologicaPredicting sinusoidal obstruction syndrome after allogeneic stem cell transplantation with the EASIX biomarker panel
79 Citations2020Sihe Jiang, Olaf Penack +9 more
EASIX-d0 is the first validated biomarker for defining a subpopulation of alloSCT recipients at high risk for SOS/VOD, and Statin/UDA endothelial prophylaxis could constitute aProphylactic measure for patients at increased SOS/ VOD risk.
Molecular and Cellular BiochemistryST2 gene expression is proliferation-dependent and its ligand, IL-33, induces inflammatory reaction in endothelial cells
79 Citations2009Shinsuke Aoki, Morisada Hayakawa +7 more
ST2 gene was expressed in each of the vascular endothelial cell types tested, and the expression was growth-dependent and down-regulated when the cells were differentiated to form vascular structures on the extracellular membrane matrix.
Bone Marrow TransplantationEndothelial cell dysfunction: a key determinant for the outcome of allogeneic stem cell transplantation
77 Citations2021Thomas Luft, Peter Dreger +1 more
The role of the endothelium in severe complications after alloSCT is delineated and the current status of search for biomarkers predicting endothelial complications, including markers of endothelial vulnerability and markers ofascular injury are described.
BMC CancerEndothelial activation and stress index (EASIX) is a reliable predictor for overall survival in patients with multiple myeloma
72 Citations2020Ga‐Young Song, Sung‐Hoon Jung +10 more
EASIX score at diagnosis is a simple and strong predictor for OS in patients with newly diagnosed MM, and in the subgroup analysis of patients who underwent ASCT, patients with high EASix showed significantly inferior OS compared to those with low EASIX.
CHEST JournalSimvastatin Suppresses Airway IL-17 and Upregulates IL-10 in Patients With Stable COPD
70 Citations2015Kittipong Maneechotesuwan, Adisak Wongkajornsilp +2 more
Simvastatin reversed the IL-17A/IL-10 imbalance in the airways and reduced sputum macrophage but not neutrophil counts in patients with COPD.
Blood Cancer JournalEASIX for prediction of survival in lower-risk myelodysplastic syndromes
69 Citations2019Almuth Maria Anni Merz, Ulrich Germing +9 more
EASIX is introduced as an easily accessible and independent predictor for survival in patients with lower-risk MDS as a significant predictor of survival after adjustment for age, sex, cytogenetic abnormalities and bone marrow blasts in lower- risk patients.
Entertaining agents
69 Citations1997Leonard N. Foner
Julia is designed to pass as human in restricted environments while being both entertaining and informative, and often elicits surprisingly intense emotional reactions in those who encounter her.
Bone Marrow TransplantationEndothelial damage is aggravated in acute GvHD and could predict its development
68 Citations2017Enrique Mir, Marta Palomo +7 more
It is demonstrated that endothelial damage is aggravated in those allo-HCT recipients developing aGvHD, and that VWF and TNFR1 are promising predictive aG vHD biomarkers, which could contribute to improve the understanding of the pathophysiology of aGVHD.
Frontiers in ImmunologyEASIX for Prediction of Outcome in Hospitalized SARS-CoV-2 Infected Patients
61 Citations2021Thomas Luft, Clemens‐Martin Wendtner +8 more
New England Journal of MedicineST2 and Endothelial Injury as a Link between GVHD and Microangiopathy
59 Citations2017Seth J. Rotz, Christopher E. Dandoy +1 more
Some patients with high ST2 levels, a marker for endothelial injury that is seen in graft-versus-host disease (GVHD), may have a response to treatment aimed at thrombotic microangiopathy.
HaematologicaEndothelial damage and dysfunction in acute graft-versus-host disease
52 Citations2020Steffen Cordes, Zeinab Mokhtari +17 more
Extensive damage, structural changes, and dysfunction of the vasculature during aGvHD are demonstrated andTherapeutic intervention by endothelium- protecting agents is an attractive approach for SR-aGv HD complementing current anti-inflammatory treatment options.
Nephrology Dialysis TransplantationStatin use after renal transplantation: a systematic quality review of trial-based evidence
46 Citations2004Krista L. Lentine, Daniel C. Brennan
Trial-based clinical evidence does not support the use of statin therapy to lower acute rejection risk after kidney transplantation, but does indicate effectiveness for improvement in cardiovascular risk markers and possibly for reduction of clinical cardiac events.
Biology of Blood and Marrow TransplantationImpact of Recipient Statin Treatment on Graft-versus-Host Disease after Allogeneic Hematopoietic Cell Transplantation
45 Citations2010Marcello Rotta, Barry E. Storer +10 more
Recipient statin treatment at the time of allogeneic HCT may decrease the risk of cGVHD in patients with cyclosporine-based postgrafting immunosuppression, but at the expense of a compromised graft-versus-tumor effect.
Journal of Clinical OncologySibling Donor and Recipient Immune Modulation With Atorvastatin for the Prophylaxis of Acute Graft-Versus-Host Disease
45 Citations2013Mehdi Hamadani, Laura F. Gibson +9 more
A novel two-pronged strategy of atorvastatin administration in both donors and recipients of matched sibling allogeneic HCT seems to be a feasible, safe, and potentially effective strategy to prevent acute GVHD.
Frontiers in ImmunologyAcute Graft-vs.-Host Disease-Associated Endothelial Activation in vitro Is Prevented by Defibrotide
38 Citations2019Julia Martínez-Sánchez, H Hamelmann +13 more
In vitro studies using endothelial cell (EC) lines found that DF significantly and dose-dependently suppressed EC proliferation and notably reduced their ability to form vascular tubes in Matrigel, supporting the view that DF has notable positive effects on endothelial biology during aGVHD.
Frontiers in ImmunologyEarly Elevation of Complement Factor Ba Is a Predictive Biomarker for Transplant-Associated Thrombotic Microangiopathy
31 Citations2021Hiroshi Okamura, Hirohisa Nakamae +16 more
Levels of Ba protein on Day 7 following allo-HSCT were abnormally and significantly higher in TA-TMA than in non-TA-Tma cases, suggesting that complement activation via the alternative pathway contributes to TA- TMA.
Biology of Blood and Marrow TransplantationAtorvastatin for the Prophylaxis of Acute Graft-versus-Host Disease in Patients Undergoing HLA-Matched Related Donor Allogeneic Hematopoietic Stem Cell Transplantation (allo-HCT)
24 Citations2015Yvonne A. Efebera, Susan Geyer +27 more
Although safe and tolerable, the addition of atorvastatin did not appear to provide any benefit to standard GVHD prophylaxis alone.
International Journal of Molecular SciencesAssociation of Soluble Suppression of Tumorigenesis-2 (ST2) with Endothelial Function in Patients with Ischemic Heart Failure
23 Citations2020Stathis Dimitropoulos, Vasiliki Chara Mystakidi +11 more
In patients with chronic HF of ischemic etiology, sST2 levels are increased and are associated with functional capacity, highlighting the interplay between the dysfunctional endothelium and HF pathophysiologic mechanisms.
TransplantationCXCL9 Predicts Severity at the Onset of Chronic Graft-versus-host Disease
23 Citations2020Nicola Giesen, Mark‐Alexander Schwarzbich +8 more
Cell Reports MedicineKynurenine pathway activation and deviation to anthranilic and kynurenic acid in fibrosing chronic graft-versus-host disease
22 Citations2021Laura Orsatti, Thomas Stiehl +8 more
Fibrosing cGVHD was associated with a distinct pathway shift toward anthranilic and kynurenic acid, correlating with reduced activity of the vitamin-B2-dependent kynurenine monooxygenase, low vitamin B6, and increased interleukin-18.
EBioMedicineInterleukin-18 and outcome after allogeneic stem cell transplantation: A retrospective cohort study
18 Citations2019Aleksandar Radujkovic, Lambros Kordelas +7 more
Higher pre-transplant levels of free IL-18 were associated with non-relapse and overall mortality after alloSCT, and may provide a rationale for prospective studies evaluating IL- 18 status and inhibition of IL-16 activity in patients undergoing allografting.
Cybernetics & SystemsTHE EPISTEMOLOGY OF AUTISM: MAKING A CASE FOR AN EMBODIED, DYNAMIC, AND HISTORICAL EXPLANATION
16 Citations1997Horst Hendriks-Jansen
It is argued that the computational model that supports the theory of mind hypothesis cannot carry its explanatory burden, and an alternative explanation based on the principles of situated robotics, ethology, and dynamical systems theory is proposed.
Annals of HematologyThe benefit of chronic graft-versus-host disease in patients with acute myeloid leukemia relapsed after allogeneic stem cell transplantation
13 Citations2019Ziwei Wang, Chunrong Yin +9 more
Current Opinion in HematologyEmerging therapeutic and preventive approaches to transplant-associated thrombotic microangiopathy
12 Citations2021Michelle Long Schoettler, Satheesh Chonat +2 more
Novel therapeutic agents for TA-TMA inhibition of the complement system are under investigation and prophylactic strategies of endothelial protection are emerging and further understanding of the pathophysiology of the disease may identify additional therapeutic targets.
Transplantation and Cellular TherapyDefibrotide Shows Efficacy in the Prevention of Sinusoidal Obstruction Syndrome After Allogeneic Hematopoietic Stem Cell Transplantation: A Retrospective Study
10 Citations2022Yves Chalandon, Anne‐Claire Mamez +12 more
A large retrospective study on SOS/VOD-prophylaxis with defibrotide suggests that this approach may be of benefit and needs to be confirmed in a prospective randomized trial.
The role of interactive conceptions of intelligence and life in cognitive technology
10 Citations2002Kerstin Dautenhahn
The paper addresses technology which aims at designing systems which are intelligent or show life like behaviour and the Embodied AL (EAL) direction is interpreted in terms of concepts which stress the individual, embodied and social nature of humans as designers and users of technology.
Lecture notes in computer scienceThe Second Person — Meaning and Metaphors
7 Citations1999Chrystopher L. Nehaniv
It is proposed that the study of agents, constructive biology, memetics and metaphor can benefit from considerations of the origin, design, evolution, and maintenance of channels of meaning for various observers and agents.
Open Research Online (The Open University)Seeing things as people: anthropomorphism and common-sense psychology
6 Citations1998Stuart Watt
It is argued that scientific theories involving the ascription of mentality through a model or a metaphor are partly dependent on each individual scientist's common-sense psychology, and that its effects are more wide ranging than is commonly thought.
BloodEasix As Prediction Score before CAR-T Cells Vs Allogeneic Hematopoietic Cell Transplantation (alloHCT) for Relapsed/Refractory (r/r) Large B Cell Lymphoma (LBCL)
4 Citations2020Felix Korell, Thomas Luft +5 more
In patients undergoing CI for r/r LBCL, EASIX measured prior to conditioning can predict mortality after both CAR-T and alloHCT, but not ifCAR-T was intended.
Annals of HematologyAcute graft-versus-host disease increase risk and accuracy in prediction model of transplantation-associated thrombotic microangiopathy in patients with myelodysplastic syndrome
3 Citations2022Ziyan Zhang, Hong Wang +7 more
A cross-validated multivariate score including aGVHD occurrence showed excellent concordance and efficacy of predicting TA-TMA in HSCT patients and predicted worsened outcomes of overall survival.
Medical Entomology and ZoologyThe inner life of children with special needs
3 Citations1996Ved P. Varma
BloodABO Incompatibility Is a Risk Factor for Intestinal Thrombotic Microangiopathy (TMA) after Allogeneic Stem Cell Transplantation.
2 Citations2004Kimikazu Matsumoto, Norio Hirabayashi +2 more
…
