Effectiveness of Antidepressant Drugs: A Triple-Blind Study Comparing Imipramine, Desipramine, and Placebo
American Journal of PsychiatryPublished 1 February 1971
Andrew Heller, RORRY ZAHOUREK, H. G. Whittington
Citations14
SJR quartileQ1
SJR score5.27
SNIP3.68
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TL;DR
The authors made a triple-blind comparison of placebo, imipramine, and desipramines in severely depressed hospitalized psychiatric patients and found that both drugs were superior to placebo.
Abstract
The authors made a triple-blind comparison of placebo, imipramine, and desipramine in severely depressed hospitalized psychiatric patients. They found that both drugs were superior to placebo, that imipramine was the drug of choice in treating these patients, and that imipramine was superior to desipramine and placebo in the rapidity of action and in the degree of improvement noted.
Keywords
MedicineNeuroscience
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