Epidermal growth factor receptor immunohistochemical reactivity in patients with American Joint Committee on Cancer Stage IV colon adenocarcinoma
CancerPublished 1 January 2001Open access
Neal S. Goldstein, M. Armin
Citations361
SJR quartileQ1
SJR score2.95
SNIP1.90
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TL;DR
The current study attempts to address background EGFR reactivity issues before determining the optimum EGFR scoring system.
Abstract
EGFR reactivity of 2+ and 3+ may provide a framework for a scoring system. It may be important to evaluate EGFR reactivity in the deepest region of tumor invasion because this region appears to contain the largest percentage of 3+ reactive cells and appears to have the strongest correlation with survival length and EGFR reactivity in lymph node and liver metastases.
Keywords
Medicine
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