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Systematic review of antihypertensive therapies: does the evidence assist in choosing a first-line drug?

PubMedPublished 13 July 1999
James M Wright, Chang‐Hoon Lee, G K Chambers
Citations144

TL;DR

Low-dose thiazide therapy can be prescribed as the first-line treatment of hypertension with confidence that the risk of death, coronary artery disease and stroke will be reduced, and was significantly better at reducing systolic blood pressure than the other drug classes.

Keywords

Decision SciencesMedicine