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Pathology grading of colon cancer surgical resection and its association with survival: a retrospective observational study

The Lancet OncologyPublished 29 July 2008
Nicholas P. West, Eva Morris, Olorunda Rotimi, Alison Cairns, P J Finan, Philip Quirke
Citations442
SJR quartileQ1
SJR score11.32
SNIP10.23

TL;DR

There is marked variability in the plane of surgery achieved in colon cancer, which might be a new cost-effective method of decreasing morbidity and mortality in patients with colon cancer.

Abstract

As previously shown in the rectum, we have now shown there is marked variability in the plane of surgery achieved in colon cancer. Improving the plane of dissection might improve survival, especially in patients with stage III disease. If confirmed by clinical trial data, such as from the ongoing National Cancer Research Institute Fluoropyrimidine, Oxaliplatin and Targeted Receptor pre-Operative Therapy for colon cancer (FOxTROT) trial of neoadjuvant chemotherapy in advanced resectable colon cancer, improvement of the plane of dissection might be a new cost-effective method of decreasing morbidity and mortality in patients with colon cancer.

Keywords

Medicine