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Multiple Versus Single Antipsychotic Agents for Hospitalized Psychiatric Patients: Case-Control Study of Risks Versus Benefits

American Journal of PsychiatryPublished 31 March 2004
Franca Centorrino, Jessica L. Gören, John Hennen, Paola Salvatore, J. Paul Kelleher, Ross J. Baldessarini
Citations249
SJR quartileQ1
SJR score5.27
SNIP3.68

TL;DR

Short-term treatment with multiple antipsychotics was associated with major increases in drug exposure, adverse events, and time in the hospital but with no apparent gain in clinical benefit, requiring further testing in controlled prospective studies.

Abstract

Short-term treatment with multiple antipsychotics was associated with major increases in drug exposure, adverse events, and time in the hospital but with no apparent gain in clinical benefit. These findings require further testing in controlled prospective studies.

Keywords

Medicine