Geographic variations in probability of pregnancy in four cities of France
Revue d Épidémiologie et de Santé PubliquePublished 1 February 2006
A. Müller, Rémy Slama, C. Labbé-Declèves, Pierre Jouannet, Louis Bujan, Roger Mieusset
Citations2
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
A possibly slightly higher fecundability in Rennes compared to Toulouse is highlighted, consistent with previous observations indicating a higher sperm concentration among semen donors in Rienne than in Toulouses.
Abstract
We highlighted a possibly slightly higher fecundability in Rennes compared to Toulouse. Possible explanations for this finding are discussed. We note that the finding is consistent with previous observations indicating a higher sperm concentration among semen donors in Rennes than in Toulouse.
Keywords
Social SciencesMedicine
Human ReproductionTesticular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects: Opinion
2,214 Citations2001N E Skakkebæk, Ewa Rajpert‐De Meyts +1 more
Environmental Health PerspectivesMale reproductive health and environmental xenoestrogens.
1,403 Citations1996Jorma Toppari, J. C. Larsen +17 more
The growing number of reports demonstrating that common environmental contaminants and natural factors possess estrogenic activity presents the working hypothesis that the adverse trends in male reproductive health may be, at least in part, associated with exposure to estrogenic or other hormonally active environmental chemicals during fetal and childhood development.
The LancetRelation between semen quality and fertility: a population-based study of 430 first-pregnancy planners
781 Citations1998Jens Peter Bonde, Erik Ernst +8 more
The study suggests that the current WHO guidelines for normal semen quality should be used with caution, as some men with sperm counts above the lower limit of the normal range defined by WHO may in fact be subfertile.
Environmental Health PerspectivesSemen quality in relation to biomarkers of pesticide exposure.
431 Citations2003Shanna H. Swan, Robin L. Kruse +8 more
American Journal of EpidemiologyUSE OF TIME TO PREGNANCY TO STUDY ENVIRONMENTAL EXPOSURES
323 Citations1986Donna D. Baird, Allen J. Wilcox +1 more
To evaluate problems with collecting data on time to pregnancy, telephone interviews were conducted with nearly 700 pregnant women who reported having planned their pregnancies and power curves indicate that relatively small sample sizes are sufficient for investigating an exposure.
Human ReproductionTime to pregnancy and semen parameters: a cross-sectional study among fertile couples from four European cities
304 Citations2002Rémy Slama
The results highlight the importance of sperm morphology parameters and indicate that the effect of proportion of normal sperm on TTP may be independent of sperm concentration.
Statistics in MedicineSources of bias in studies of time to pregnancy
214 Citations1994Clarice R. Weinberg, Donna D. Baird +1 more
Models for analysing time-to-pregnancy data are described, seven sources of bias that can lead the reproductive epidemiologist to spurious conclusions are discussed, and certain analytic and design strategies can help protect against some of the pitfalls.
Human ReproductionRegional differences in waiting time to pregnancy: pregnancy-based surveys from Denmark, France, Germany, Italy and Sweden
177 Citations1999Svend Juul
The study shows that smoking, body mass index, age and parity did not explain the differences in fecundity found between the centres, and regional differences in FEC exist.
BiometricsA Discrete Survival Model with Random Effects: An Application to Time to Pregnancy
143 Citations1997Thomas Scheike, Tina Kold Jensen
A discrete survival model that allows time-dependent covariates was constructed and a random effect was included to account for unobserved heterogeneity.
Human ReproductionEvidence for regional differences of semen quality among fertile French men. Federation Francaise des Centres d'Etude et de Conservation des Oeufs et du Sperme humains
116 Citations1997Jacques Auger, Pierre Jouannet
This is the first study providing evidence for regional differences in the human semen quality, with significant differences found between centres for seminal volume, sperm concentration, total number of spermatozoa in the ejaculate and percentage of motile spermutozoa.
Human ReproductionRegional differences in waiting time to pregnancy among fertile couples from four European cities
95 Citations2001Tina Kold Jensen, Rémy Slama +14 more
The observed geographical differences in TTP remain unexplained and were not due to differences in semen quality, but may be caused by varying exposures to environmental factors or psychological distress.
The LancetDecreased fertility in Britain compared with Finland
83 Citations1996Michael Joffe
The previously reported difference in sperm counts between Finland and elsewhere in northwest Europe (including Britain) is probably not artefactual, suggesting that the reported world-wide decline in semen quality is also real.
European Journal of Public HealthInfertility and subfecundity in population-based samples from Denmark, Germany, Italy, Poland and Spain
75 Citations1999Wilfried Karmaus
Important differences in the prevalence of subfecundity exist between the six European regions investigated and comparisons should first consider TUI or planned TUI to reduce the impact of distorting factors which are mainly due to differing cultures of family planning in Europe.
EpidemiologyHow Would a Decline in Sperm Concentration Over Time Influence the Probability of Pregnancy?
53 Citations2004Rémy Slama, Tina Kold Jensen +4 more
The effect of realistic declines in sperm concentration on time to pregnancy may be observed only with studies that include several thousand couples, and these studies had much lower statistical power and were biased toward the null.
Human ReproductionSelection bias in semen studies due to self-selection of volunteers
48 Citations2004A. Müller, Élise de La Rochebrochard +9 more
This study demonstrates the existence of selection bias in semen studies associated with fertility and socio-demographic characteristics of men.
Annals of the New York Academy of SciencesSelection Bias Associated with Contraceptive Practice in Time‐to‐Pregnancy Studies
42 Citations1994Donna D. Baird, Clarice R. Weinberg +2 more
In studies of subfertility using data on time to pregnancy, many pregnancies are not included in analyses because time-to-pregnancy data cannot always be collected, and the more fecund couples are more likely to have birth control failures, the more likely they are to be excluded from analyses.
Human ReproductionFecundity in Thai and European regions: results based on waiting time to pregnancy
37 Citations1998P Tuntiseranee, Joy E. Olsen +2 more
This study has illustrated that cross-culture comparison of subfecundity is difficult despite using a common protocol and questionnaire because of differences in the use of contraceptive methods and a different concept of pregnancy planning.