Normative data for the EORTC QLQ-C30 and EORTC-sexuality items in the general Dutch population
European Journal of CancerPublished 5 December 2010Open access
Lonneke V. van de Poll‐Franse, Floortje Mols, Chad M. Gundy, Carien L. Creutzberg, Remi A. Nout, Irma M. Verdonck‐de Leeuw
Citations212
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
Dutch men and women reported high levels of overall QoL as compared to previously published Scandinavian and German normative data, and men scored statistically but never clinically significantly better on most functional scales than women.
Abstract
Age, gender and other health problems are important when comparing QoL and sexuality among different cancer cohorts. Normative data on QoL and sexuality are needed to interpret QoL issues among the growing group of (long-term) cancer survivors.
Keywords
Social SciencesMedicine
PsychometrikaCoefficient Alpha and the Internal Structure of Tests
43,211 Citations1951Lee J. Cronbach
JNCI Journal of the National Cancer InstituteThe European Organization for Research and Treatment of Cancer QLQ-C30: A Quality-of-Life Instrument for Use in International Clinical Trials in Oncology
15,964 Citations1993N.K. Aaronson, Sam H. Ahmedzai +17 more
The reliability and validity of the EORTC QLQ-C30 questionnaire were highly consistent across the three language-cultural groups studied: patients from English-speaking countries, Northern Europe, and Southern Europe.
Journal of Clinical OncologyInterpreting the significance of changes in health-related quality-of-life scores.
2,944 Citations1998David Osoba, George Rodrigues +3 more
The significance of changes in QLQ-C30 scores can be interpreted in terms of small, moderate, or large changes in quality of life as reported by patients in the SSQ.
Arthritis Care & ResearchThe self‐administered comorbidity questionnaire: A new method to assess comorbidity for clinical and health services research
1,829 Citations2003Oliver Sangha, Gerold Stucki +3 more
The SCQ has modest correlations with a widely used medical record-based comorbidity instrument, and with subsequent health status and utilization, and it will be particularly useful in settings where medical records are unavailable.
Quality of Life ResearchMeasurement of the quality of life in cancer survivors
688 Citations1995Betty Ferrell, K. Hassey Dow +1 more
It is demonstrated that the QOL-CS and its subscales adequately measured QOL in this growing population of cancer survivors.
Journal of Clinical OncologyImpact of Late Treatment-Related Toxicity on Quality of Life Among Patients With Head and Neck Cancer Treated With Radiotherapy
688 Citations2008Johannes A. Langendijk, Patricia Doornaert +4 more
Late radiation-induced toxicity, particularly RTOG (swallowing) and RTOG(xerostomia), has a significant impact on the more general dimensions of HRQoL, and the development of new radiation- induced delivery techniques should not only focus on reduction of the dose to the salivary glands, but also on anatomic structures that are involved in swallowing.
European Journal of CancerReference data for the quality of life questionnaire EORTC QLQ-C30 in the general German population
510 Citations2001R Schwarz, Andreas Hinz
The results show that age and sex differences must be taken into consideration when different groups of cancer patients are compared and the norm values help to interpret quality of life data for clinicians.
Journal of Medical Internet ResearchInternet Versus Mailed Questionnaires: A Randomized Comparison
428 Citations2004Philip L. Ritter, Kate Lorig +2 more
Among a convenience sample recruited via the Internet, results from those randomly assigned to Internet participation were at least as good as, if not better than, among those assigned mailed questionnaires, with less recruitment effort required.
Acta OncologicaHealth-related Quality of Life Measured by the EORTC QLQ-C30: Reference Values From a Large Sample of the Swedish Population
381 Citations2000Christina Bolund Helena Michelson
The oldest respondents (70-79 years) had a greater degree of impaired HRQOL than the other age groups, with one exception, 'Emotional functioning', in which they scored higher.
Critical Reviews in Oncology/HematologyPrognostic impact of increasing age and co-morbidity in cancer patients: A population-based approach
380 Citations2005M.L.G. Janssen‐Heijnen, Saskia Houterman +4 more
In general, elderly did not suffer from more complications than younger patients, except for cardiac complications (colorectal cancer and NHL) and postoperative death (non-small cell lung cancer) and for most tumours relative survival was lower for the elderly,except for patients with colon cancer, prostate cancer or indolent NHL.
Journal of Clinical OncologyHealth-related quality of life in the general Norwegian population assessed by the European Organization for Research and Treatment of Cancer Core Quality-of-Life Questionnaire: the QLQ=C30 (+ 3).
367 Citations1998Marianne Jensen Hjermstad, Peter Fayers +2 more
This is the first study that presented reference data from the EORTC QLQ-C30 in a sample from a general population and seems to provide valid measures of HRQOL within different age groups, and contributes to a better understanding of the significance of mean scores and their clinical relevance.
European Journal of CancerInterpreting quality of life data
293 Citations2001Peter Fayers
There are substantial differences between Germany and Scandinavia for many of the scales, especially the symptom items and scales in which Germans report fewer problems, and these differences are discussed by Schwartz and Hinz.
European Journal of CancerUsing reference data on quality of life—the importance of adjusting for age and gender, exemplified by the EORTC QLQ-C30 (+3)
286 Citations1998Marianne Jensen Hjermstad, Peter Fayers +2 more
The derivation of age- and gender-specific 'expected' values from population reference values by means of simple calculations is demonstrated, and how to generate mean values which are adjusted according to the age and gender distribution of a population is demonstrated.
Journal of Clinical OncologyQuality of Life After Pelvic Radiotherapy or Vaginal Brachytherapy for Endometrial Cancer: First Results of the Randomized PORTEC-2 Trial
272 Citations2009Remi A. Nout, Hein Putter +12 more
Patients who received EBRT reported significantly higher levels of diarrhea and bowel symptoms, which resulted in a higher need to remain close to a toilet and, as a consequence, more limitation of daily activities because of bowel symptoms and decreased social functioning.
CancerQuality of life and sexual problems in disease‐free survivors of cervical cancer compared with the general population
245 Citations2007Sangyoon Park, Duk‐Soo Bae +8 more
The purpose of this study was to identify problems related to long‐term quality of life (QOL) and sexual function in cervical cancer survivors.
Journal of Medical Internet ResearchPsychological Assessment via the Internet: A Reliability and Validity Study of Online (vs Paper-and-Pencil) Versions of the General Health Questionnaire-28 (GHQ-28) and the Symptoms Check-List-90-Revised (SCL-90-R)
212 Citations2007Miguel A. Vallejo, Carlos M. Jordán Cristóbal +3 more
This work analyzed the online versions of two popular psychopathology screening questionnaires and suggests that both online questionnaires were fairly equivalent to their paper-and-pencil versions, with higher reliability values for the SCL-90-R.
Psycho-OncologyAssessing the impact of cancer: development of a new instrument for long‐term survivors
148 Citations2005Brad Zebrack, Patricia A. Ganz +3 more
A new instrument that measures aspects of long‐term survivorship not measured by existing tools is developed and evaluated.
Quality of Life ResearchQuality of life of Danish women: Population-based norms for the EORTC QLQ-C30
135 Citations1997M. Klee, M. Groenvold +1 more
Drawing population-based norms for women completing the EORTC QLQ-C30 version 1 is recommended both as an aid to the clinical assessment of an individual patient, and to assist in the interpretation of clinical trial and longitudinal quality of life data.
Seminars in Oncology NursingSexuality: A Quality-of-Life Issue for Cancer Survivors
129 Citations2008D. Kathryn Tierney
Nurses and other health care professions can begin to help cancer survivors adapt to changes in sexuality related to cancer and cancer treatment by initiating a discussion of sexuality at the time of diagnosis and throughout the trajectory of disease.
JNCI Journal of the National Cancer InstituteRefinement and Psychometric Evaluation of the Impact of Cancer Scale
119 Citations2008Catherine M. Crespi, Patricia A. Ganz +3 more
The IOCv2 scales provide a validated tool for measuring the impact of cancer on quality of life in long-term cancer survivors and patterns of association between IOC v2 scale scores and CES-D and BCPT scores indicated good concurrent validity.
Annals of Surgical OncologyQuality of Life After Axillary or Groin Sentinel Lymph Node Biopsy, With or Without Completion Lymph Node Dissection, in Patients With Cutaneous Melanoma
104 Citations2009M. de Vries, Harald J. Hoekstra +1 more
QoL in melanoma survivors after axillary or inguinal SLNB with or without CLND was better than that in a norm group and by comparing QoL between four patient groups depending on surgical procedure and location.
Journal of Clinical OncologyHealth-Related Quality of Life in Long-Term Survivors of Testicular Cancer
91 Citations2009Philip Rossen, Anette Fischer Pedersen +2 more
The results suggest that patients treated for TC should be informed about the anticipated good post-therapeutic QOL and the low risk of psychosocial and physical long-term effects.
Journal of Clinical OncologyCurrent and Future Utilization of Services From Medical Oncologists
90 Citations2008Joan L. Warren, Angela B. Mariotto +3 more
Utilization of oncologists' services will increase appreciably between 2005 and 2020; this will be driven predominantly by an increase in survivors of cancer and by the aging of the population.
Acta OncologicaStability of health-related quality of life in the Norwegian general population and impact of chronic morbidity in individuals with and without a cancer diagnosis
77 Citations2007Sophie D. Fosså, Siri Lothe Hess +3 more
As common chronic co-morbidity significantly impairs HRQoL in cancer survivors, prevention of adverse health conditions represents a major challenge in such survivors and in the interpretation of HRQeL incancer survivors’ co- Morbid conditions and socio-demographic variables must be considered.
JNCI Journal of the National Cancer InstituteCase-Control Studies of Cancer Screening: Theory and Practice
74 Citations1998Kathleen A. Cronin, Robert Connor +2 more
This review summarizes methodologic theories for the design of cancer screening case-control studies and examines the methods applied in studies published in English from 1980 through 1996, finding methodologic theory and practice to be consistent.
Journal of Surgical OncologyLong‐term survivors of esophageal cancer: Disease‐specific quality of life, general health and complications
60 Citations2009Ines Gockel, U. Gönner +3 more
The aim of this study was to assess the quality of life as well as secondary cancers/diseases and esophagectomy‐related or unrelated interventions in the long‐term course of surgery.
The Journal of UrologyOn the Importance of Race, Socioeconomic Status and Comorbidity When Evaluating Quality of Life in Men With Prostate Cancer
57 Citations2007Scott D. Ramsey, Steven B. Zeliadt +3 more
Most of the available prostate cancer health related quality of life literature does not describe or does not account for factors known to influence health outcomes, and omissions limit their interpretability for patients trying to make decisions about treatment.
Supportive Care in CancerCo-morbidity and functional deficits independently contribute to quality of life before chemotherapy in elderly cancer patients
54 Citations2007Ulrich Wedding, Bernd Röhrig +4 more
IADL contributes to global QoL in addition to the known effect of KPS, and co-morbidity independently influences global QOL in elderly cancer patients.
UrologyDoes “Normal” Aging Imply Urinary, Bowel, and Erectile Dysfunction? A General Population Survey
45 Citations2008Ida J. Korfage, Monique J. Roobol +4 more
Urinary and bowel dysfunction were not part of the "normal" aging process and erectile dysfunction was significantly more prevalent in older men, in men treated for localized prostate cancer.
Journal of Women s HealthThe Sexual Activity Questionnaire: Pychometric Properties And Normative Data in A Norwegian Population Sample
40 Citations2007Ingvild Vistad, Sophie D. Fosså +3 more
The Sexual Activity Questionnaire is a short and discrete screening tool for sexual function, with good psychometric properties, and changes with age as to pleasure, habit, and discomfort confirmed construct validity of the SAQ-F.