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Efficacy of a prophylactic adjuvanted bivalent L1 virus-like-particle vaccine against infection with human papillomavirus types 16 and 18 in young women: an interim analysis of a phase III double-blind, randomised controlled trial

The LancetPublished 1 June 2007
Jorma Paavonen, David Jenkins, F. Xavier Bosch, Paulo Naud, Jorge Salmerón, Cosette M. Wheeler
Citations1,300
SJR quartileQ1
SJR score12.11
SNIP22.72

TL;DR

The adjuvanted HPV16/18 vaccine showed prophylactic efficacy against cervical intraepithelial neoplasia (CIN) 2+ associated with HPV16 or HPV18 and thus could be used for cervical cancer prevention.

Abstract

The adjuvanted HPV16/18 vaccine showed prophylactic efficacy against CIN2+ associated with HPV16 or HPV18 and thus could be used for cervical cancer prevention.

Keywords

Immunology and MicrobiologyMedicine