A strategy of DNA sequencing employing computer programs
Nucleic Acids ResearchPublished 1 January 1979Open access
Rodger Staden
Citations394
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TL;DR
Computer programs that can be used to order both sequence gel readings and clones are described and a method of coding for uncertainties in gel readings is described.
Abstract
With modern fast sequencing techniques and suitable computer programs it is now possible to sequence whole genomes without the need of restriction maps. This paper describes computer programs that can be used to order both sequence gel readings and clones. A method of coding for uncertainties in gel readings is described. These programs are available on request.
Keywords
Biochemistry, Genetics and Molecular Biology
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183 Citations1978Rodger Staden
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