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Chronic antioxidant treatment improves sympathetic functions and β-adrenergic pathway in the spontaneously hypertensive rats

Journal of HypertensionPublished 1 January 2003
Hélène Girouard, Chantal Chulak, M LEJOSSEC, Daniel Lamontagne, Jacques de Champlain
Citations70
SJR quartileQ1
SJR score1.10
SNIP1.63

TL;DR

It is suggested that NAC and melatonin decreased the MAP and heart rate and improved the chronotropic response to isoproterenol in SHRs, in association with an inhibition of sympathetic activity and the restoration of cardiac β-adrenoceptor function.

Abstract

These results suggest that NAC and melatonin decreased the MAP and heart rate and improved the chronotropic response to isoproterenol in SHRs, in association with an inhibition of sympathetic activity and the restoration of cardiac beta-adrenoceptor function.

Keywords

MedicineNeuroscience