Fatigue life of compact bone—I effects of stress amplitude, temperature and density
Journal of BiomechanicsPublished 1 January 1976
D.R. Carter, Wilson C. Hayes
Citations186
SJR quartileQ1
SJR score0.80
SNIP1.22
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
Fatigue tests to failure of compact adult bovine bone specimens were conducted at five stress amplitudes and four temperature levels which span the physiologic range of bone temperature in the human foot.
Abstract
Fatigue tests to failure of compact adult bovine bone specimens were conducted at five stress amplitudes (65–108 MN/m2) and four temperature levels (21–45°C) which span the physiologic range of bone temperature in the human foot. After testing, determinations were made of specimen density and microstructure and fracture surfaces were examined by scanning electron microscopy. The test results demonstrated highly significant (P < 0·01) negative correlations between fatigue life and stress amplitude and between fatigue life and temperature. A highly significant positive correlation between fatigue life and bone density was also shown. The microstructure studies indicated that primary compact bone has a longer fatigue life than secondary Haversian bone. A multiple regression analysis was used to derive an equation for fatigue life as a function of stress amplitude, temperature and bone density. This statistically derived equation correlates well with previous fatigue studies of human compact bone.
Keywords
MedicineEngineering
Acta Orthopaedica ScandinavicaFactors Affecting the Determination of the Physical Properties of Femoral Cortical Bone
581 Citations1966Elias D. Sedlin, Carl Hirsch
Journal of BiomechanicsThe response of joints to impact loading — II In vivo behavior of subchondral bone
237 Citations1972Sheldon R. Simon, Eric L. Radin +2 more
The knee joints of live guinea pigs, subjected to repeated longitudinal impaction, developed obvious cartilage degeneration over a 3 week period, Associated with, and slightly preceding the earliest cartilage changes, as judged histochemically, was a stiffening of the underlying subchondral bone.
Journal of the American Medical AssociationPhysiology of Heat Regulation and the Science of Clothing
236 Citations1950
Journal of BiomechanicsThe temperature dependence of the deformation of bone
152 Citations1968W. Bonfield, C.H. Li
The deformation characteristics of compact bone have been measured as a function of temperature in the range from −58 to 90°C and an interpretation of these results is made in terms of an idealised hydroxyapatite-collagen composite.
Journal of BiomechanicsMechanical and morphological aspects of experimental overload and fatigue in bone
150 Citations1970A. Chamay
The author reports the results of experiments in which long bone fatigue is produced in 30 pairs of dog ulnas by applying opposing forces at both extremities thereby causing a strain.
Journal of Bone and Joint Surgery - British VolumeISOLATED TRABECULAR FATIGUE FRACTURES IN THE FEMORAL HEAD
111 Citations1972R. C. Todd, M. A. R. Freeman +1 more
It is suggested that excessive cyclical loading, sometimes leading to fatigue fractures, may represent a fundamental pathological process of general importance in the evolution of certain skeletal and articular diseases.
Journal of Applied PhysicsDeformation and Fracture of Bone
101 Citations1966W. Bonfield, Chien‐Wei Li
Medical & Biological Engineering & ComputingThe fatigue properties of human cortical bone
78 Citations1971S. A. V. Swanson, M. A. R. Freeman +1 more
The usual inverse relationship between stress amplitude and fatigue life was found; the median life was 1·3×104 cycles at a stress amplitude of 12,200 1bf/in2 and 4·6×106 cycles at 6750 1bf/.
Mechanical Stress, Functional Adaptation and the Variation Structure of the Human Femur Diaphysis
67 Citations1971E. Amtmann
Factor Analysis of the Variation Structure of Human Femur Cross-sections finds that the Femur Compacta to Fluctuating Bending Stresses by Means of Specific Distribution of Anisotropic Bone Material is a major cause of variation in size, shape, and structure in Femur Diaphysis.
PubMedCollagen fibre patterns in mammalian bone.
67 Citations1960James W. Smith
In this investigation, a somewhat different classification has been found to be advantageous, based on three factors, namely, the relationship of neighbouring fibres to one another, their relationship to vascular channels, and the place occupied by the tissue in the developmental history of the skeleton as a whole.
PubMedRelations between the fatigue life and histology of adult human cortical bone.
55 Citations1970F. Gaynor Evans, Michael L. Riolo
Journal of Bone and Joint SurgeryRelations between the Fatigue Life and Histology of Adult Human Cortical Bone
54 Citations1970F. Gaynor Evans, Michael L. Riolo
Journal of Applied Physiology<i>Strength of Human Compact Bone Under Repetitive Loading</i>
49 Citations1957F. Gaynor Evans, Milton Lebow
The fatigue life, under a constant load of 5000 lb/in, was determined for 67 specimens of compact bone of a standardized size obtained from five above-knee amputations.
Journal of Bone and Joint Surgery - British VolumeEXPERIMENTAL FATIGUE FRACTURE OF THE HUMAN CADAVERIC FEMORAL NECK
41 Citations1971Wyn Griffiths, S. A. V. Swanson +1 more
It is inferred that some femoral neck fractures in the elderly may be fatigue fractures caused by the cyclic loading of normal walking.
Medical & Biological Engineering & ComputingOn the origin of scatter in results of human bone strenght tests
28 Citations1970J. C. Wall, S. Chatterji +1 more
A list of factors which may influence the result of strength tests on bone is given and discussed and it is suggested that by careful consideration of these factors and by standardization of the variables among them, the scatter of results could be reduced.
Journal of Applied PhysiologyStrength of human metatarsal bones under repetitive loading
27 Citations1959Glenn O'D. Lease, F. Gaynor Evans
The fatigue life of 51 intact human metatarsals was tested in a Sonntag Flexure Fatigue machine equipped with an automatic counter and shutoff.
Medical & Biological Engineering & ComputingHuman femoral cortical bone: A preliminary report on the relationship between strength and density
19 Citations1972J. C. Wall, S. Chatterji +1 more
A graph of strength against density shows that density is not the sole factor in determining bone strength, although there is a general trend of increasing strength with increasing density, and other factors must be taken into account to explain variation in bone strength.