Tumor Necrosis Factor and Steroid Metabolism in Chronic Heart Failure: Possible Relation to Muscle Wasting
Journal of the American College of CardiologyPublished 1 October 1997
Stefan D. Anker, Andrew L. Clark, Michael Kemp, Colin Salsbury, Mauro Martins Teixeira, Paul G. Hellewell
Citations191
SJR quartileQ1
SJR score9.02
SNIP6.30
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TL;DR
There is an increase in TNF and its soluble receptors in chronic heart failure associated with a rise in the cortisol/DHEA (catabolic/anabolic) ratio, which correlates with BMI and clinical severity of heart failure, suggesting a possible etiologic link.
Abstract
There is an increase in TNF and its soluble receptors in chronic heart failure. This increase is associated with a rise in the cortisol/DHEA (catabolic/anabolic) ratio. These changes correlate with BMI and clinical severity of heart failure, suggesting a possible etiologic link.
Keywords
Medicine
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