login

Resistance to reinfection with Schistosoma mansoni in occupationally exposed adults and effect of HIV-1 co-infection on susceptibility to schistosomiasis: a longitudinal study

The LancetPublished 1 August 2002
Diana M. S. Karanja, Allen W. Hightower, Daniel G. Colley, Pauline N. M. Mwinzi, Karin Galil, Julius Andove
Citations141
SJR quartileQ1
SJR score12.11
SNIP22.72

TL;DR

Immunological resistance to reinfection with S mansoni exists or can develop independent of age effects, and the consequence of HIV-1 co-infection suggests that CD4 T cells contribute to this resistance.

Abstract

Adults similarly exposed to schistosomiasis are either resistant to reinfection; susceptible, but develop resistance to reinfection after multiple treatments; or remain susceptible to reinfection. Thus, immunological resistance to reinfection with S mansoni exists or can develop independent of age effects. The consequence of HIV-1 co-infection suggests that CD4 T cells contribute to this resistance.

Keywords

Immunology and MicrobiologySocial SciencesMedicine