login

Conformation of twisted β-pleated sheets in proteins

Journal of Molecular BiologyPublished 1 April 1973
Cyrus Chothia
Citations493
SJR quartileQ1
SJR score2.21
SNIP1.13

Abstract

It is shown that β-pleated sheets with a right-hand twist when viewed along the polypeptide chain direction have a lower free energy than sheets that are straight or which have a left-hand twist. This result is discussed with reference to the observed conformations of β-pleated sheets in proteins.

Keywords

Materials ScienceBiochemistry, Genetics and Molecular Biology