mentha: a resource for browsing integrated protein-interaction networks
Nature MethodsPublished 30 July 2013
Alberto Calderone, Luisa Castagnoli, Gianni Cesareni
Citations360
SJR quartileQ1
SJR score17.25
SNIP8.40
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
Systems-level approaches require access to comprehensive genome-wide and proteome-wide databases and a comprehensive resource that archives all published protein-protein interactions (PPIs) is not available.
Abstract
Systems-level approaches require access to comprehensive \ngenome-wide and proteome-wide databases. A comprehensive \nresource that archives all published protein-protein interactions \n(PPIs) is not available. In fact, primary PPI databases capture \nonly a fraction of published data.
Keywords
Biochemistry, Genetics and Molecular Biology
Nucleic Acids ResearchMINT, the molecular interaction database: 2012 update
1,057 Citations2011Luana Licata, Leonardo Briganti +10 more
The growth of the database, the major changes in curation policy and a new algorithm to assign a confidence to each interaction are reported here.
Nature BiotechnologyThe HUPO PSI's Molecular Interaction format—a community standard for the representation of protein interaction data
638 Citations2004Henning Hermjakob, Luisa Montecchi‐Palazzi +37 more
This work proposes a community standard data model for the representation and exchange of protein interaction data, jointly developed by members of the Proteomics Standards Initiative (PSI) and the Human Proteome Organization (HUPO).
Nature MethodsProtein interaction data curation: the International Molecular Exchange (IMEx) consortium
574 Citations2012Sandra Orchard, Samuel Kerrien +29 more
The International Molecular Exchange consortium is an international collaboration between major public interaction data providers to share literature-curation efforts and make a nonredundant set of protein interactions available in a single search interface on a common website.
Nature MethodsPSICQUIC and PSISCORE: accessing and scoring molecular interactions
299 Citations2011Bruno Aranda, Hagen Blankenburg +38 more
To study proteins in the context of a cellular system, it is essential that the molecules with which a protein interacts are identified and the functional consequence of each interaction is understood.
FEBS JournalHuPho: the human phosphatase portal
62 Citations2012Susanna Liberti, Francesca Sacco +9 more
A website designed to facilitate the retrieval of information about human protein phosphatases and a text‐mining‐assisted annotation effort aimed at extracting phosphatase related data reported in the scientific literature are presented.