Birth asphyxia and cerebral palsy.
BMJPublished 29 July 1989Open access
David Hall
Citations53
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The resource implications of repeatedly screening all patients aged over 50 with dyspepsia are daunting, but only with a drive toward early diagnosis and, probably to a lesser extent, better surgery may the results of treating gastric cancer be improved.
Keywords
Medicine
Archives of NeurologyNeonatal Encephalopathy Following Fetal Distress
2,627 Citations1976Harvey B. Sarnat
Twenty-one neonates of over 36 weeks' gestation suffered perinatal asphyxia but not chronic hypoxia; three clinical stages of postanoxic encephalopathy were distinguished; persistence of stage 2 for more than seven days or failure of the EEG to revert to normal was associated with later neurologic impairment or death.
New England Journal of MedicineAntecedents of Cerebral Palsy
943 Citations1986Karin B. Nelson, Jonas H. Ellenberg
American Journal of Obstetrics and GynecologyThe Dublin randomized controlled trial of intrapartum fetal heart rate monitoring
628 Citations1985Dermot MacDonald, Adrian Grant +3 more
Cases of neonatal seizures and persistent abnormal neurological signs followed by survival were twice as frequent in the intermittent auscultation group, and this differential effect was related to duration of labor.
The Journal of PediatricsMonozygotic twinning and structural defects
529 Citations1979Albert Schinzel, David W. Smith +1 more
The finding of both discordant and concordant MZ twins with Goldenhar, de Lange, and Rubinstein-Taybi syndromes suggests that these "syndromes" might be early malformation complexes.
The Journal of PediatricsIntrapartum asphyxia: A rare cause of cerebral palsy
514 Citations1988Eve Blair, Fiona Stanley
The contribution of intrapartum events and obstetric mismanagement to overall cerebral palsy rates is probably less than was previously thought.
New England Journal of MedicineBirth and the Origins of Cerebral Palsy
438 Citations1986Nigel Paneth
"Cerebral palsy" is a descriptive term for a collection of nonprogressive neuromotor disorders of central origin that become manifest early in life and are not the result of a recognized cerebral malformation.
BMJPrenatal asphyxia, hyperlacticaemia, hypoglycaemia, and erythroblastosis in growth retarded fetuses.
370 Citations1987P. W. Soothill, K. H. Nicolaides +1 more
The severity of fetal hypoxia correlated significantly with fetal hypercapnia, acidosis, hyperlacticaemia, hypoglycaemia, and erythroblastosis, indicating that "birth asphyxia" is not necessarily due to the process of birth.
Developmental Medicine & Child NeurologyTERM INFANTS WITH HYPOXIC‐ISCHEMIC ENCEPHALOPATHY: OUTCOME AT 3.5 YEARS
330 Citations1985Charlene M.T. Robertson, Neil Finer
In term infants with documented HIE at birth, major neurodevelopmental dysfunction at 3–5 years depended more on prospectively established category of HIE than on other perinatal or social factors.
BMJPerinatal brain damage: predictive value of metabolic acidosis and the Apgar score.
305 Citations1988Vineta Ruth, Kari O. Raivio
Metabolic acidosis determined in blood from the umbilical artery at birth is a poor predictor of perinatal brain damage, and the positive predictive value of low pH for adverse outcome is found.
The LancetCOMPARISON OF TWO METHODS OF PREDICTING OUTCOME IN PERINATAL ASPHYXIA
295 Citations1986Malcolm I. Levene, Helen Grindulis +2 more
In a follow-up study of 122 full-term infants in whom postasphyxial encephalopathy occurred the incidence of death or severe handicap was 1 in 1000 deliveries and the abilities of two methods of diagnosing intrapartum asphyxia to predict outcome at a median age of 2.5 years were compared.
Early Human DevelopmentThe incidence and severity of post-asphyxial encephalopathy in full-term infants
290 Citations1985Malcolm L. Levene, J. Kornberg +1 more
The incidence of clinically significant birth asphyxia was assessed over a 4-year period in a busy teaching hospital maternity hospital and there is some evidence that the incidence of this condition has not changed over a 10 year period.
The LancetCEREBRAL ARTERY DOPPLER ULTRASONOGRAPHY FOR PREDICTION OF OUTCOME AFTER PERINATAL ASPHYXIA
201 Citations1986L N Archer, Malcolm I. Levene +1 more
American Journal of Obstetrics and GynecologyCerebral palsy and mental retardation in relation to indicators of perinatal asphyxia
136 Citations1983Nigel Paneth, Raymond I. Stark
It is suggested that resuscitative efforts in mature newborn infants ought not to be too quickly abandoned for fear of late sequelae, and that the most appropriate justification for antenatal and intrapartum monitoring of fetal condition are the established associations of indicators of fetal asphyxia with fetal and neonatal death, and with morbidity in the neonatal period.
The Journal of PediatricsMulticystic encephalomalacia in liveborn twin with a stillborn macerated co-twin
115 Citations1979Hiroshi Yoshioka, Yoko Kadomoto +4 more
Computed tomography showed multiple cystic lesions in the brains of three infants with cerebral palsy, each patient was the product of a twin pregnancy with a stillborn, macerated co-twin.
Human GeneticsLinkage studies of X-linked recessive spastic paraplegia using DNA probes
109 Citations1986Susan Kenwrick, Victor Ionâşescu +5 more
A family with six males affected by X-linked spastic paraplegia (McKusick No. 31290) is described, which was accompanied by mental retardation in all patients and by absence of extensor pollicis longus in four cases.
The LancetADVERSE OUTCOME OF PREGNANCY AND THE QUALITY OF OBSTETRIC CARE
103 Citations1984Kenneth R. Niswander, Diana Elbourne +5 more
Fetuses whose deaths were ascribed to asphyxia or trauma, and babies born at term who had seizures within 48 h of delivery, were significantly more likely than controls to have received suboptimal care during pregnancy.
Archives of NeurologyIntracranial Hemorrhage in the Term Newborn
84 Citations1984Gerald M. Fenichel, David Webster +1 more
Over a five-year period, 22 term newborns with intracranial hemorrhage by computed tomography in an intensive care unit for newborns were identified and primary subarachnoid hemorrhage (diffuse or focal) was the most common type of hemorrhage.
Journal of neurosurgeryNeonatal intracranial hemorrhage
78 Citations1980Richard Leblanc, Augustin M. O’Gorman
Computerized tomography is a useful adjunct to the diagnosis, management, and follow-up study of neonatal intracranial hemorrhage, and correlates well with the clinical findings.
Biology of the NeonateFetal Encephalopathies of Circulatory Origin
66 Citations2009Jeanne‐Claudie Larroche
With generalized ultrasonography of the fetus, the lesions can be detected in utero and subsequent neurological handicaps of the infants will no longer be attributed to difficult labor and birth.
BJOG An International Journal of Obstetrics & GynaecologyVery early neonatal seizure rate: a possible epidemiological indicator of the quality of perinatal care
63 Citations1982Jennifer H. Dennis, Iain Chalmers
It is proposed that the frequency of neonatal seizures beginning within 48 h of birth should be considered as an index which may meet these criteria in respect of full‐term babies.
American Journal of Obstetrics and GynecologyFetal heart rate patterns and development in the first year of life
58 Citations1978Michael J. Painter, Richard Depp +1 more
The development of 50 high-risk infants who were provided intrauterine monitoring during labor was prospectively evaluated, and the duration of ominous fetal heart rate patterns appears to adversely affect development.
Archives of Disease in ChildhoodCause of neonatal convulsions. Towards more precise diagnosis.
40 Citations1986M I Levene, J Q Trounce
All infants presenting with neonatal seizures over a two year period were carefully investigated for the cause and in 20% either intracranial haemorrhage or infarction of a major cerebral artery was detected by real time ultrasound.
American Journal of Obstetrics and GynecologyThe effect of intrauterine hypoxia on the child surviving to 4 years
38 Citations1975Kenneth R. Niswander, Myron Gordon +1 more
Children of low birth weight in either group experienced lower I. Q. scores and higher risk of abnormal findings on the motor tests at 4 years than the babies of mature birth weight.
BJOG An International Journal of Obstetrics & GynaecologyA paediatrician asks—why is it called birth injury?
29 Citations1985Ronald S. Illingworth
There is an interaction of numerous factors, prenatal, perinatal and postnatal and it is simplistic to ascribe ‘brain damage’ to single factors, such as breech delivery or hypoxia at birth, without considering the antecedent causes of those factors.
American Journal of Obstetrics and GynecologyIntrapartum fetal asphyxia: A preliminary report in regard to long-term morbidity
22 Citations1978James A. Low, R.S. Galbraith +4 more
Results have not as yet indicated that the mature fetus with at least a terminal episode of asphyxia will exhibit evidence of handicap due to central nervous system injury.
Archives of Disease in ChildhoodClinical factors associated with adverse outcome for babies weighing 2000 g or less at birth.
20 Citations1988Neil Marlow, Laura Hunt +1 more
It is postulate that certain impairments arise independently of clinical events, although most occur in children who had complicated perinatal courses.
Journal of Paediatrics and Child HealthClinical spectrum and outcome of neonatal convulsions
19 Citations1988David Tudehope, Anthony Harris +2 more
The clinical spectrum and outcome of neonatal convulsions within an obstetric hospital population were reviewed for the 5 years, 1978–82, inclusive and tonic seizures had the highest mortality and morbidity.
Archives of Disease in ChildhoodSpastic hemiparesis and presumed prenatal embolisation.
16 Citations1988A A Asindi, John B.P. Stephenson +1 more
An infant with clinical evidence of prenatal right subclavian arterial occlusion subsequently developed left hemiparesis with cystic infarction of the territory of the right middle cerebral artery, which may be a warning of possible simultaneous cerebral infarctions.
Survey of AnesthesiologyComparison of Two Methods of Predicting Outcome in Perinatal Asphyxia
13 Citations1986Malcolm I. Levene, Helen Grindulis +2 more