West Nile Encephalitis in Israel, 1999: The New York Connection
Emerging infectious diseasesPublished 1 August 2001Open access
Michael Giladi, Einat Metzkor‐Cotter, Denise A. Martin, Yardena Siegman‐Igra, Amos D. Korczyn, Raffaele Rosso
Citations48
SJR quartileQ1
SJR score1.88
SNIP1.47
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
Abstract
We describe two cases of West Nile (WN) encephalitis in a married couple in Tel Aviv, Israel, in 1999. Reverse transcription-polymerase chain reaction performed on a brain specimen from the husband detected a WN viral strain nearly identical to avian strains recovered in Israel in 1998 (99.9% genomic sequence homology) and in New York in 1999 (99.8%). This result supports the hypothesis that the 1999 WN virus epidemic in the United States originated from the introduction of a strain that had been circulating in Israel.
Keywords
MedicineBiochemistry, Genetics and Molecular Biology
ScienceOrigin of the West Nile Virus Responsible for an Outbreak of Encephalitis in the Northeastern United States
1,615 Citations1999Robert S. Lanciotti, John T. Roehrig +22 more
In late summer 1999, an outbreak of human encephalitis occurred in the northeastern United States that was concurrent with extensive mortality in crows (Corvus species) as well as the deaths of several exotic birds at a zoological park in the same area.
Journal of Clinical MicrobiologyRapid Detection of West Nile Virus from Human Clinical Specimens, Field-Collected Mosquitoes, and Avian Samples by a TaqMan Reverse Transcriptase-PCR Assay
1,116 Citations2000Robert S. Lanciotti, Amy J. Kerst +10 more
The TaqMan assay was specific for WN virus and demonstrated a greater sensitivity than the traditional RT-PCR method and correctly identified WNirus in 100% of the culture-positive mosquito pools and 98% ofthe culture- positive avian tissue samples.
Journal of Clinical MicrobiologyStandardization of Immunoglobulin M Capture Enzyme-Linked Immunosorbent Assays for Routine Diagnosis of Arboviral Infections
480 Citations2000Denise A. Martin, David A. Muth +4 more
This work has evaluated and standardized a combined MAC-ELISA capable of identifying virus infections caused by members of each virus family, and determined that a 1:400 serum dilution is most appropriate for screening antiviral antibody.
PubMedOutbreak of West Nile-like viral encephalitis--New York, 1999.
235 Citations1999
The cause of the outbreak of arboviral encephalitis was confirmed as a West Nile-like virus based on the identification of virus in human, avian, and mosquito samples.
Journal of Clinical MicrobiologyDetection of Anti-Arboviral Immunoglobulin G by Using a Monoclonal Antibody-Based Capture Enzyme-Linked Immunosorbent Assay
216 Citations2000Alison J. Johnson, Denise A. Martin +2 more
The tests were standardized for laboratory diagnosis of arboviral infections, with the intent that they be used in tandem with the corresponding IgM antibody-capture ELISAs, and correlated with those of the standard plaque-reduction neutralization assays.
The LancetGenetic analysis of West Nile New York 1999 encephalitis virus
182 Citations1999Xi-Yu Jia, Thomas Briese +7 more
Analysis of the genome of the flavivirus responsible for the 1999 New York City encephalitis epidemic cloned from human brain by reverse-transcription polymerase chain reaction indicates its identity as a lineage I West Nile virus (WNV; WNV-NY1999) closely related to WNVs previously isolated In the Middle East.
