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West Nile Encephalitis in Israel, 1999: The New York Connection

Emerging infectious diseasesPublished 1 August 2001Open access
Michael Giladi, Einat Metzkor‐Cotter, Denise A. Martin, Yardena Siegman‐Igra, Amos D. Korczyn, Raffaele Rosso
Citations48
SJR quartileQ1
SJR score1.88
SNIP1.47
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Abstract

We describe two cases of West Nile (WN) encephalitis in a married couple in Tel Aviv, Israel, in 1999. Reverse transcription-polymerase chain reaction performed on a brain specimen from the husband detected a WN viral strain nearly identical to avian strains recovered in Israel in 1998 (99.9% genomic sequence homology) and in New York in 1999 (99.8%). This result supports the hypothesis that the 1999 WN virus epidemic in the United States originated from the introduction of a strain that had been circulating in Israel.

Keywords

MedicineBiochemistry, Genetics and Molecular Biology