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Testing Vulnerability Models: Stability of Potential Vulnerability Indicators Across Clinical State

Published 1 January 1990
Keith H. Nuechterlein, Michael E. Dawson, Joseph Ventura, David L. Fogelson, Michael Gitlin, Jim Mintz
Citations49

TL;DR

Seasonal measures that reveal abnormalities during the acute psychotic episode and then return to normal levels during nonpsychotic, clinically remitted periods are called episode indicators, because they index processes that show acute disruptions during the psychotic period.

Abstract

In recent years, several researchers have proposed a distinction between vulnerability indicators (or markers) and episode indicators for schizophrenic disorders, based on whether an abnormality is present only during the active psychotic state or on a continuing basis (Zubin and Spring 1977; Cromwell and Spaulding 1978). Measures that reveal abnormalities during the acute psychotic episode and then return to normal levels during nonpsychotic, clinically remitted periods are called episode indicators, because they index processes that show acute disruptions during the psychotic period. Episode indicators would be expected to include (1) abnormalities that reflect processes immediately underlying the acute psychotic symptoms and (2) abnormalities that are secondary to disruptions associated with acute psychotic symptoms.

Keywords

PsychologyMedicineArts and Humanities