Moonlighting proteins
Trends in Biochemical SciencesPublished 1 January 1999
Constance J. Jeffery
Citations1,056
SJR quartileQ1
SJR score4.16
SNIP2.34
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Abstract
The idea of one gene--one protein--one function has become too simple because increasing numbers of proteins are found to have two or more different functions. The multiple functions of such moonlighting proteins add another dimension to cellular complexity and benefit cells in several ways. However, cells have had to develop sophisticated mechanisms for switching between the distinct functions of these proteins.
Keywords
Biochemistry, Genetics and Molecular Biology
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