Eukaryotic DNA replication: yeast bares its ARSs
Trends in Biochemical SciencesPublished 1 June 1988
Judith L. Campbell
Citations22
SJR quartileQ1
SJR score4.16
SNIP2.34
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TL;DR
In addition to ARSs, a "reverse genetics" analysis of proteins involved in yeast replication is aiding in elucidating mechanisms of eukaryotic DNA replication.
Abstract
The isolation of yeast autonomously replicating sequences (ARSs) and their identification as origins of replication has focused attention on yeast as the only eukaryotic system in which a single chromosomal replicon can be studied in detail. In addition to ARSs, a “reverse genetics” analysis of proteins involved in yeast replication is aiding in elucidating mechanisms of eukaryotic DNA replication.
Keywords
Biochemistry, Genetics and Molecular Biology
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