Reduced brain serotonin transporter availability in major depression as measured by [123I]-2β-carbomethoxy-3β-(4-iodophenyl)tropane and single photon emission computed tomography
Biological PsychiatryPublished 1 December 1998
Robert T. Malison, Lawrence H. Price, Robert Berman, Christopher H. van Dyck, Gregory H. Pelton, Linda L. Carpenter
Citations499
SJR quartileQ1
SJR score4.68
SNIP2.24
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TL;DR
These data are the first to suggest reductions in the density of brain SERT binding sites in living depressed patients and provide further support for a preeminent role for alterations in serotonergic neurons in the pathophysiology of depression.
Abstract
These data are the first to suggest reductions in the density of brain SERT binding sites in living depressed patients. These findings provide further support for a preeminent role for alterations in serotonergic neurons in the pathophysiology of depression.
Keywords
Neuroscience
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