login

Prognostic significance of tumoral angiogenesis in completely resected late stage lung carcinoma (Stage IIIA-N2): Impact of adjuvant therapies in a subset of patients at high risk of recurrence

CancerPublished 1 August 1996Open access
Carlo Alberto Angeletti, Marco Lucchi, Gabriella Fontanini, Alfredo Mussi, Antonio Chella, Alessandro Ribechini
Citations70
SJR quartileQ1
SJR score2.95
SNIP1.90
View PDF

TL;DR

Microvessel count, as a measure of tumor angiogenesis, has been significantly correlated with metastatic disease in cutaneous, mammary, prostatic, head and neck, and early stage lung carcinoma.

Abstract

Our results provide evidence that neovascularization, estimated by the MC, can predict metastatic disease and survival in patients with completely resected T1-3N2M0 NSCLC, and may also be useful in patient selection for effective adjuvant treatment.

Keywords

MedicineBiochemistry, Genetics and Molecular Biology