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Hypothalamic and Extrahypothalamic Distribution of CRF-Like Immunoreactive Neurons in the Rat Brain

NeuroendocrinologyPublished 26 March 2008
John A. Olschowka, Thomas L. O’Donohue, Gregory P. Mueller, David M. Jacobowitz
Citations179
SJR quartileQ2
SJR score1.09
SNIP0.96

TL;DR

Using an antiserum to synthetic ovine corticotropin-releasing factor (CRF), CRF-like immunoreactive neurons were observed in the central nervous system of normal and colchicine-treated rats.

Abstract

Using an antiserum to synthetic ovine corticotropin-releasing factor (CRF), CRF-like immunoreactive neurons were observed in the central nervous system of normal and colchicine-treated rats. CRF immunoreactivity was observed in the hypothalamus, thalamus, amygdala, cerebral cortex, midbrain, pons medulla, cerebellum and spinal cord. The significance of the extrahypothalamic distribution of CRF-like immunoreactivity is unknown.

Keywords

MedicineNeuroscience