Novel tartrate-derived guanidine-catalyzed highly enantio- and diastereoselective Michael addition of 3-substituted oxindoles to nitroolefins
Chemical CommunicationsPublished 1 January 2014
Li‐Wei Zou, Xinhe Bao, Yuanyuan Ma, Yuming Song, Jingping Qü, Baomin Wang
Citations45
SJR quartileQ1
SJR score1.04
SNIP0.78
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TL;DR
The Michael addition of 3-substituted oxindoles to nitroolefins was catalyzed by a novel tartrate-derived guanidine in high yield with excellent diastereo- and enantioselectivity.
Abstract
The Michael addition of 3-substituted oxindoles to nitroolefins was catalyzed by a novel tartrate-derived guanidine in high yield with excellent diastereo- and enantioselectivity. This method showed an extraordinarily broad substrate scope in terms of both reaction partners.
Keywords
ChemistryBiochemistry, Genetics and Molecular Biology
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