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Multiple prostate cancer risk variants on 8q24

Nature GeneticsPublished 25 April 2007
John S. Witte
Citations117
SJR quartileQ1
SJR score16.59
SNIP6.64

TL;DR

Three new reports leverage genome-wide studies to localize and replicate multiple independent variants strongly associated with prostate cancer on chromosome 8q24, providing a significant advance toward deciphering the genetic basis of this disease.

Abstract

Three new reports leverage genome-wide studies to localize and replicate multiple independent variants strongly associated with prostate cancer on chromosome 8q24. These findings provide a significant advance toward deciphering the genetic basis of this disease, although further work is needed to clarify the biological mechanisms underlying these associations.

Keywords

MedicineBiochemistry, Genetics and Molecular Biology