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Memory consolidation: Brain region and neurotransmitter specificity

Neuroscience LettersPublished 1 September 1983
Raymond P. Kesner, Maureen E. Ellis
Citations23
SJR quartileQ2
SJR score0.77
SNIP0.67

TL;DR

The data provide evidence for brain region-neurotransmitter specificity which supports a multiple component hypothesis and helps to explain why post-trial injections of norepinephrine into the amygdala produce a long-term retention deficit in rats.

Abstract

Post-trial injections of norepinephrine, but not dopamine, into the amygdala produce a long-term retention deficit (amnesia) for a 1-trial footshock experience in rats. In contrast, post-trial injections of dopamine, but not norepinephrine, into the caudate produce long-term facilitation. The data provide evidence for brain region-neurotransmitter specificity which supports a multiple component hypothesis.

Keywords

Neuroscience