Memory consolidation: Brain region and neurotransmitter specificity
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TL;DR
The data provide evidence for brain region-neurotransmitter specificity which supports a multiple component hypothesis and helps to explain why post-trial injections of norepinephrine into the amygdala produce a long-term retention deficit in rats.
Abstract
Post-trial injections of norepinephrine, but not dopamine, into the amygdala produce a long-term retention deficit (amnesia) for a 1-trial footshock experience in rats. In contrast, post-trial injections of dopamine, but not norepinephrine, into the caudate produce long-term facilitation. The data provide evidence for brain region-neurotransmitter specificity which supports a multiple component hypothesis.
