The public health importance of hookworm disease
ParasitologyPublished 1 October 2000
D. W. T. Crompton
Citations199
SJR quartileQ1
SJR score0.63
SNIP1.01
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
Abstract
The public health significance of hookworm disease is briefly reviewed. The latest evidence confirms that blood loss caused by the worms' feeding activity in the gut is a contributing factor in the development of poor iron status leading to iron-deficiency anaemia. The World Health Organization has identified adolescent girls and women of child-bearing age as high-risk groups regarding the impact of hookworm disease. The merits of treating pregnant women with anthelminthic drugs after the first trimester are discussed.
Keywords
Immunology and MicrobiologyMedicineNursing
World development report 1993 : investing in health
2,419 Citations1993Seth Berkley, Jose‐Luis Bobadilla +7 more
This report examines the controversial questions surrounding health care and health policy and advocates a threefold approach to health policy for governments in developing countries and in the formerly socialist countries, based in large part on innovative research.
Transactions of the Royal Society of Tropical Medicine and HygieneInfectious diseases of humans
2,182 Citations1992Adrian Hall
PubMedStrategies and tools for the control/elimination of lymphatic filariasis.
627 Citations1997Eric A. Ottesen, B. O. L. Duke +2 more
New approaches to disease control, based on preventing bacterial superinfection, can now halt or even reverse the lymphoedema and elephantiasis sequelae of filarial infection.
Trends in Ecology & Evolution(Meta)population dynamics of infectious diseases
543 Citations1997Bryan T. Grenfell
The metapopulation concept provides a very powerful tool for analysing the persistence of spatially-disaggregated populations, in terms of a balance between local extinction and colonization.
Parasitology TodayBench aids for the diagnosis of intestinal parasites
294 Citations1995Richard L. Guerrant
ParasitologyThe evaluation of potential global morbidity attributable to intestinal nematode infections
284 Citations1994M.S. Chan, Graham F. Medley +2 more
The estimates presented here indicate that several tens of millions of children are likely to suffer developmental consequences from infection, and suggest that the global disease burden of geohelminthiasis may be significantly greater than was supposed.
Advances in Parasitology/Advances in parasitologyControl Strategies for Human Intestinal Nematode Infections
211 Citations1999Marco Albonico, D. W. T. Crompton +1 more
Highly effective and safety-tested, single-dose anthelminthic drugs are now available, permitting periodical deworming of schoolchildren and other high-risk groups at affordable prices, and several well-monitored country experiences have shown that chemotherapy-based control of morbidity due to soil-transmitted helminths is possible and highly cost-effective.
SciencePredisposition to Hookworm Infection in Humans
191 Citations1985G. A. Schad, Roy M. Anderson
Analyses of individual post-treatment patterns of hookworm reinfection among 112 villagers in an endemic area of West Bengal provide quantitative evidence of predisposition to heavy infection.
Journal of NutritionWeight Gain of Kenyan School Children Infected with Hookworm, Trichuris trichiura and Ascaris lumbricoides is Improved Following Once- or Twice-Yearly Treatment with Albendazole
176 Citations1993Lani S. Stephenson, Michael C Latham +3 more
It is concluded that one or two doses of albendazole per year resulted in similar growth improvements, despite reinfection, in school-age children in an area where these helminths and poor growth are prevalent.
American Journal of Tropical Medicine and HygieneHemoquant Determination of Hookworm-Related Blood Loss and Its Role in Iron Deficiency in African Children
153 Citations1996Rebecca J. Stoltzfus, Marco Albonico +5 more
The prevalence of iron deficiency anemia increased steadily as hookworm infection intensity and intestinal blood loss increased, and determination of fecal heme is a useful tool for measuring the impact of hookworm control activities.
ParasitologyHookworm infections and human iron metabolism
92 Citations1993D. W. T. Crompton, R R Whitehead
A mathematical model is proposed to explain how human iron metabolism may respond to hookworm infection of varying intensity, drawing attention to the importance of the regulation of stored iron levels in the process.
ParasitologyInfection, nutrition and cognitive performance in children
88 Citations1993Kevin Connolly, Jane Kvalsvig
The information processing model of human cognition is outlined and IQ and DQ are explained and a speculative hypothesis concerning the psychological effects of parasitic infection is sketched.
The population dynamics and control of hookworm and roundworm infections
85 Citations1982Roy M. Anderson
More than thirty years ago Stoll (1947) noted that helminth parasites were amongst the most prevalent of all human infections within many tropical, subtropical and temperate regions of the world.
Journal of the American Medical AssociationAnimal Agents and Vectors of Human Disease
54 Citations1955
ParasitologyHelminths and the transmammary route of infection
39 Citations1981Grover C. Miller
The transmammary transmission of larvae is a viable alternative in the life-cycles of a number of helminths, and in some instances it is probably the major route of infection.
Journal of NutritionIron: Nutrition Monitoring and Nutrition Status Assessment
38 Citations1990Mary Ann Johnson
The red cell distribution width (RDW) appears to be elevated to a greater extent in iron deficiency than in chronic disease or thalassemia traits, and RDW and CRP are two of several indicators of iron status in the third National Health and Examination Survey (NHANES III).
Transactions of the Royal Society of Tropical Medicine and HygieneBlood loss in chronic schistosoma mansoni infection in egyptian farmers
30 Citations1967Farid Zand, S. Bassily +5 more
In spite of continued blood loss, 3 patients with severe iron deficiency anaemia responded rapidly, clinically and haematogically, to oral iron treatment.
Transactions of the Royal Society of Tropical Medicine and HygieneHookworm infection and intestinal blood loss
23 Citations1967Carlos Martínez-Torres, A. Ojeda +2 more
Egg counts are better correlated with blood loss than total parasite counts and as expected with the total number of females, and the extent to which hookworms are responsible for iron deficiency anemia in an endemic area may be presumed from egg counts.
PubMedIntestinal parasitic infections in Campalagian district, south Sulawesi, Indonesia.
12 Citations1993Andarias Mangali, P Sasabone +6 more
Prevalence of lavatories among houses appeared to be inversely proportional to the prevalence of hookworm infection, while the incomplete structure of the lavatories might result in contamination of environment with Ascaris and Trichuris eggs.
PubMedZinc in the pathogenesis of hookworm anaemia.
5 Citations1984S Migasena, J Sumetchotimaytha +2 more
The results showed that the serum zinc levels in anaemic patients with hookworm infection were significantly lower than those of the controls (p less than 0.01).