Improved Oxygenation and Lower Peak Airway Pressure in Severe Adult Respiratory Distress Syndrome

CHEST JournalPublished 1 February 1986

Michael J. Gurevitch, John Van Dyke, Earl Young, Ken Jackson

DOI10.1378/chest.89.2.211

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Citations149

SJR quartileQ1

SJR score1.83

SNIP1.83

TL;DR

Two patients with the adult respiratory distress syndrome were placed on pressure-controlled inverse-ratio ventilation when their condition deteriorated despite optimal treatment with intermittent mandatory ventilation and positive end-expiratory pressure, showing that IRV may offer certain advantages in the treatment of severe ARDS.

Abstract

Two patients with the adult respiratory distress syndrome (ARDS) were placed on pressure-controlled inverse-ratio ventilation (IRV) when their condition deteriorated despite optimal treatment with intermittent mandatory ventilation and positive end-expiratory pressure. In the first case, high peak airway pressure was reduced by 50 percent with the institution of IRV. In the second, refractory hypoxemia was eliminated by using an inspiratory-to-expiratory ratio of 4:1. These cases show that IRV may offer certain advantages in the treatment of severe ARDS.

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